Propofol and postoperative infections

To the Editor: Bennett et al.1 report on thorough investigations into postoperative infections associated with the use of the intravenous anesthetic propofol, but we would like to add some comments. Clusters of fever episodes, infections, or sepsis associated with propofol use were reported exclusiv...

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Bibliographic Details
Main Authors: Bach, Alfons (Author) , Geiss, Heinrich K. (Author)
Format: Article (Journal) Editorial
Language:English
Published: November 30, 1995
In: The New England journal of medicine
Year: 1995, Volume: 333, Issue: 22, Pages: 1505-1506
ISSN:1533-4406
DOI:10.1056/NEJM199511303332216
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1056/NEJM199511303332216
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Author Notes:Alfons Bach, Heinrich Konrad Geiss

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520 |a To the Editor: Bennett et al.1 report on thorough investigations into postoperative infections associated with the use of the intravenous anesthetic propofol, but we would like to add some comments. Clusters of fever episodes, infections, or sepsis associated with propofol use were reported exclusively in the United States shortly after the approval of this drug by the Food and Drug Administration. Epidemiologic studies conducted subsequently implicated extrinsic contamination of propofol infusions with various microorganisms.2 Although the epidemiologic data constitute convincing indirect evidence that the infectious episodes stemmed from contamination of propofol through the improper use of aseptic techniques, in no . . . 
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