UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae)
A crude methanol extract of the roots of Allochrusa gypsophiloides (syn. Acanthophyllum gypsophiloides) (collected from the Tashkent region of Uzbekistan) was chemically characterised by UHPLC-ESI-QTOF-MS/MS analysis. The results indicate the presence of six major bisdesmosidic saponins derived from...
Gespeichert in:
| Hauptverfasser: | , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
23 Sep 2023
|
| In: |
Natural product research
Year: 2023, Pages: 1-5 |
| ISSN: | 1478-6427 |
| DOI: | 10.1080/14786419.2023.2260068 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1080/14786419.2023.2260068
|
| Verfasserangaben: | Rano Mamadalieva, Vaxobjon Xujayev, Farukh S. Sharopov & Michael Wink |
MARC
| LEADER | 00000caa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1871777275 | ||
| 003 | DE-627 | ||
| 005 | 20240307035431.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 231201s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/14786419.2023.2260068 |2 doi | |
| 035 | |a (DE-627)1871777275 | ||
| 035 | |a (DE-599)KXP1871777275 | ||
| 035 | |a (OCoLC)1425209102 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 32 |2 sdnb | ||
| 100 | 1 | |a Mamadalieva, Rano |e VerfasserIn |0 (DE-588)1297878108 |0 (DE-627)1854058002 |4 aut | |
| 245 | 1 | 0 | |a UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae) |c Rano Mamadalieva, Vaxobjon Xujayev, Farukh S. Sharopov & Michael Wink |
| 264 | 1 | |c 23 Sep 2023 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 01.12.2023 | ||
| 520 | |a A crude methanol extract of the roots of Allochrusa gypsophiloides (syn. Acanthophyllum gypsophiloides) (collected from the Tashkent region of Uzbekistan) was chemically characterised by UHPLC-ESI-QTOF-MS/MS analysis. The results indicate the presence of six major bisdesmosidic saponins derived from gypsogenin, gypsogenic and quillaic acids, including five compounds reported for the first time for this species. The chloroform, methanol and water extracts of A. gypsophiloides showed weak antioxidant and anthelmintic activities. Among the tested extracts, the water extract exhibited the highest level of cytotoxicity in CCRF-CEM and CEM/ADR5000 cell lines with IC50 values of 23.6 and 31.9 µg/mL, respectively. | ||
| 650 | 4 | |a Allochrusa gypsophiloides | |
| 650 | 4 | |a anthelmintic | |
| 650 | 4 | |a antioxidant | |
| 650 | 4 | |a cytotoxic | |
| 650 | 4 | |a triterpene saponins | |
| 650 | 4 | |a UHPLC-MS (ultra-high performance liquid-chromatography) | |
| 700 | 1 | |a Xujayev, Vaxobjon |e VerfasserIn |4 aut | |
| 700 | 1 | |a Sharopov, Farukh |e VerfasserIn |0 (DE-588)1067605487 |0 (DE-627)819008419 |0 (DE-576)426789016 |4 aut | |
| 700 | 1 | |a Wink, Michael |d 1951- |e VerfasserIn |0 (DE-588)124618146 |0 (DE-627)363448519 |0 (DE-576)164659390 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Natural product research |d London [u.a.] : Taylor & Francis, 2003 |g (2023), Seite 1-5 |h Online-Ressource |w (DE-627)484658565 |w (DE-600)2185747-7 |w (DE-576)275076989 |x 1478-6427 |7 nnas |a UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae) |
| 773 | 1 | 8 | |g year:2023 |g pages:1-5 |g extent:5 |a UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae) |
| 856 | 4 | 0 | |u https://doi.org/10.1080/14786419.2023.2260068 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20231201 | ||
| 993 | |a Article | ||
| 994 | |a 2023 | ||
| 998 | |g 124618146 |a Wink, Michael |m 124618146:Wink, Michael |d 160000 |d 160100 |e 160000PW124618146 |e 160100PW124618146 |k 0/160000/ |k 1/160000/160100/ |p 4 |y j | ||
| 999 | |a KXP-PPN1871777275 |e 4424151867 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"relHost":[{"title":[{"title":"Natural product research","title_sort":"Natural product research"}],"origin":[{"publisherPlace":"London [u.a.]","dateIssuedKey":"2003","dateIssuedDisp":"2003-","publisher":"Taylor & Francis"}],"note":["Gesehen am 03.04.2023"],"part":{"text":"(2023), Seite 1-5","year":"2023","extent":"5","pages":"1-5"},"id":{"zdb":["2185747-7"],"issn":["1478-6427"],"eki":["484658565"]},"physDesc":[{"extent":"Online-Ressource"}],"language":["eng"],"disp":"UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae)Natural product research","recId":"484658565","type":{"bibl":"periodical","media":"Online-Ressource"},"pubHistory":["17.2003 -"]}],"note":["Gesehen am 01.12.2023"],"type":{"media":"Online-Ressource","bibl":"article-journal"},"id":{"doi":["10.1080/14786419.2023.2260068"],"eki":["1871777275"]},"physDesc":[{"extent":"5 S."}],"language":["eng"],"title":[{"title":"UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae)","title_sort":"UHPLC-MS characterisation of principal triterpene glycosides and biological activities of different solvent extracts of Allochrusa gypsophiloides (Caryophyllaceae)"}],"recId":"1871777275","origin":[{"dateIssuedDisp":"23 Sep 2023","dateIssuedKey":"2023"}],"name":{"displayForm":["Rano Mamadalieva, Vaxobjon Xujayev, Farukh S. Sharopov & Michael Wink"]},"person":[{"role":"aut","given":"Rano","display":"Mamadalieva, Rano","family":"Mamadalieva"},{"family":"Xujayev","given":"Vaxobjon","display":"Xujayev, Vaxobjon","role":"aut"},{"role":"aut","family":"Sharopov","display":"Sharopov, Farukh","given":"Farukh"},{"given":"Michael","display":"Wink, Michael","family":"Wink","role":"aut"}]} | ||
| SRT | |a MAMADALIEVUHPLCMSCHA2320 | ||