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HIV‐1 infection of CD4 T cells impairs antigen‐specific B cell function

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Failures to produce neutralizing antibodies upon HIV‐1 infection result in part from B‐cell dysfunction due to unspecific B‐cell activation. How HIV‐1 affects antigen‐specific B‐cell functions remains elusive. Using an adoptive transfer mouse model and ex vivo HIV infection of human tonsil tissue, w...

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Main Authors: Kaw, Sheetal (Author) , Ananth, Swetha (Author) , Tsopoulidis, Nikolaos (Author) , Morath, Katharina (Author) , Coban, Bahar M (Author) , Hohenberger, Ralph (Author) , Bulut, Cem (Author) , Klein, Florian (Author) , Stolp-Rastätter, Bettina (Author) , Fackler, Oliver Till (Author)
Format: Article (Journal)
Language:English
Published: 4 November 2020
In: The EMBO journal
Year: 2020, Volume: 39, Issue: 24, Pages: 1-18
ISSN:1460-2075
DOI:10.15252/embj.2020105594
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.15252/embj.2020105594
Verlag, lizenzpflichtig, Volltext: https://www.embopress.org/doi/full/10.15252/embj.2020105594
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Author Notes:Sheetal Kaw, Swetha Ananth, Nikolaos Tsopoulidis, Katharina Morath, Bahar M Coban, Ralph Hohenberger, Olcay C Bulut, Florian Klein, Bettina Stolp & Oliver T Fackler
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HIV-1 infection of CD4 T cells impairs antigen-specific B cell function by Kaw, Sheetal (Author) , Ananth, Swetha (Author) , Tsopoulidis, Nikolaos (Author) , Morath, Katharina (Author) , Coban, Bahar M. (Author) , Hohenberger, Ralph (Author) , Bulut, Cem (Author) , Klein, Florian (Author) , Stolp-Rastätter, Bettina (Author) , Fackler, Oliver Till (Author) ,


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