Impact of time point of extracorporeal membrane oxygenation on mortality and morbidity in congenital diaphragmatic hernia: a single-center case series

Since there are no data available on the influence of the time point of ECMO initiation on morbidity and mortality in patients with congenital diaphragmatic hernia (CDH), we investigated whether early initiation of ECMO after birth is associated with a beneficial outcome in severe forms of CDH. All...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Wegele, Christian (VerfasserIn) , Schreiner, Yannick (VerfasserIn) , Perez Ortiz, Alba (VerfasserIn) , Hetjens, Svetlana (VerfasserIn) , Otto, Christiane (VerfasserIn) , Boettcher, Michael (VerfasserIn) , Schaible, Thomas (VerfasserIn) , Rafat, Neysan (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 1 July 2022
In: Children
Year: 2022, Jahrgang: 9, Heft: 7, Pages: 1-8
ISSN:2227-9067
DOI:10.3390/children9070986
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/children9070986
Verlag, kostenfrei, Volltext: https://www.mdpi.com/2227-9067/9/7/986
Volltext
Verfasserangaben:Christian Wegele, Yannick Schreiner, Alba Perez Ortiz, Svetlana Hetjens, Christiane Otto, Michael Boettcher, Thomas Schaible and Neysan Rafat

MARC

LEADER 00000caa a2200000 c 4500
001 187638493X
003 DE-627
005 20240307080915.0
007 cr uuu---uuuuu
008 231219s2022 xx |||||o 00| ||eng c
024 7 |a 10.3390/children9070986  |2 doi 
035 |a (DE-627)187638493X 
035 |a (DE-599)KXP187638493X 
035 |a (OCoLC)1425215810 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Wegele, Christian  |d 1988-  |e VerfasserIn  |0 (DE-588)1136627995  |0 (DE-627)893329975  |0 (DE-576)490713882  |4 aut 
245 1 0 |a Impact of time point of extracorporeal membrane oxygenation on mortality and morbidity in congenital diaphragmatic hernia  |b a single-center case series  |c Christian Wegele, Yannick Schreiner, Alba Perez Ortiz, Svetlana Hetjens, Christiane Otto, Michael Boettcher, Thomas Schaible and Neysan Rafat 
264 1 |c 1 July 2022 
300 |a 8 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Dieser Artikel gehört zum Special issue: Pediatric intensive care – practice and research) 
500 |a Gesehen am 19.12.2023 
520 |a Since there are no data available on the influence of the time point of ECMO initiation on morbidity and mortality in patients with congenital diaphragmatic hernia (CDH), we investigated whether early initiation of ECMO after birth is associated with a beneficial outcome in severe forms of CDH. All neonates with CDH admitted to our institution between 2010 until 2020 and undergoing ECMO treatment were included in this study and divided into four different groups: (1) ECMO initiation < 12 h after birth (n = 143), (2) ECMO initiation between 12-24 h after birth (n = 31), (3) ECMO initiation between 24-120 h after birth (n = 48) and (4) ECMO initiation > 120 h after birth (n = 14). The mortality rate in the first (34%) and fourth group (43%) was high and in the second group (23%) and third group (12%) rather low. The morbidity, characterized by chronic lung disease (CLD), did not differ significantly in the three groups; only patients in which ECMO was initiated >120 h after birth had an increased rate of severe CLD. Our data, although not randomized and limited due to small study groups, suggest that very early need for ECMO and ECMO initiation > 120 h after birth is associated with increased mortality. 
650 4 |a chronic lung disease 
650 4 |a congenital diaphragmatic hernia 
650 4 |a extracorporeal membrane oxygenation 
700 1 |a Schreiner, Yannick  |d 1994-  |e VerfasserIn  |0 (DE-588)1299964346  |0 (DE-627)1857691237  |4 aut 
700 1 |a Perez Ortiz, Alba  |d 1985-  |e VerfasserIn  |0 (DE-588)1198239018  |0 (DE-627)1680557831  |4 aut 
700 1 |a Hetjens, Svetlana  |d 1983-  |e VerfasserIn  |0 (DE-588)1031801979  |0 (DE-627)737600284  |0 (DE-576)379534223  |4 aut 
700 1 |a Otto, Christiane  |d 1979-  |e VerfasserIn  |0 (DE-588)131377442  |0 (DE-627)508494575  |0 (DE-576)298438313  |4 aut 
700 1 |a Boettcher, Michael  |d 1982-  |e VerfasserIn  |0 (DE-588)138309566  |0 (DE-627)696492113  |0 (DE-576)306510219  |4 aut 
700 1 |a Schaible, Thomas  |d 1960-  |e VerfasserIn  |0 (DE-588)1026440440  |0 (DE-627)726733342  |0 (DE-576)371782333  |4 aut 
700 1 |a Rafat, Neysan  |d 1979-  |e VerfasserIn  |0 (DE-588)137475748  |0 (DE-627)695829815  |0 (DE-576)303079487  |4 aut 
773 0 8 |i Enthalten in  |t Children  |d Basel : MDPI, 2013  |g 9(2022), 7, Artikel-ID 986, Seite 1-8  |h Online-Ressource  |w (DE-627)768093007  |w (DE-600)2732685-8  |w (DE-576)393634949  |x 2227-9067  |7 nnas  |a Impact of time point of extracorporeal membrane oxygenation on mortality and morbidity in congenital diaphragmatic hernia a single-center case series 
773 1 8 |g volume:9  |g year:2022  |g number:7  |g elocationid:986  |g pages:1-8  |g extent:8  |a Impact of time point of extracorporeal membrane oxygenation on mortality and morbidity in congenital diaphragmatic hernia a single-center case series 
856 4 0 |u https://doi.org/10.3390/children9070986  |x Verlag  |x Resolving-System  |z kostenfrei  |3 Volltext 
856 4 0 |u https://www.mdpi.com/2227-9067/9/7/986  |x Verlag  |z kostenfrei  |3 Volltext 
951 |a AR 
992 |a 20231219 
993 |a Article 
994 |a 2022 
998 |g 137475748  |a Rafat, Neysan  |m 137475748:Rafat, Neysan  |d 60000  |d 60001  |e 60000PR137475748  |e 60001PR137475748  |k 0/60000/  |k 1/60000/60001/  |p 8  |y j 
998 |g 1026440440  |a Schaible, Thomas  |m 1026440440:Schaible, Thomas  |d 60000  |d 62300  |e 60000PS1026440440  |e 62300PS1026440440  |k 0/60000/  |k 1/60000/62300/  |p 7 
998 |g 138309566  |a Boettcher, Michael  |m 138309566:Boettcher, Michael  |d 60000  |d 62200  |e 60000PB138309566  |e 62200PB138309566  |k 0/60000/  |k 1/60000/62200/  |p 6 
998 |g 131377442  |a Otto, Christiane  |m 131377442:Otto, Christiane  |d 60000  |d 61300  |e 60000PO131377442  |e 61300PO131377442  |k 0/60000/  |k 1/60000/61300/  |p 5 
998 |g 1031801979  |a Hetjens, Svetlana  |m 1031801979:Hetjens, Svetlana  |d 60000  |d 60200  |d 60250  |e 60000PH1031801979  |e 60200PH1031801979  |e 60250PH1031801979  |k 0/60000/  |k 1/60000/60200/  |k 2/60000/60200/60250/  |p 4 
998 |g 1198239018  |a Perez Ortiz, Alba  |m 1198239018:Perez Ortiz, Alba  |d 60000  |d 62500  |e 60000PP1198239018  |e 62500PP1198239018  |k 0/60000/  |k 1/60000/62500/  |p 3 
998 |g 1299964346  |a Schreiner, Yannick  |m 1299964346:Schreiner, Yannick  |d 60000  |e 60000PS1299964346  |k 0/60000/  |p 2 
999 |a KXP-PPN187638493X  |e 4440800599 
BIB |a Y 
SER |a journal 
JSO |a {"title":[{"title":"Impact of time point of extracorporeal membrane oxygenation on mortality and morbidity in congenital diaphragmatic hernia","subtitle":"a single-center case series","title_sort":"Impact of time point of extracorporeal membrane oxygenation on mortality and morbidity in congenital diaphragmatic hernia"}],"language":["eng"],"origin":[{"dateIssuedDisp":"1 July 2022","dateIssuedKey":"2022"}],"name":{"displayForm":["Christian Wegele, Yannick Schreiner, Alba Perez Ortiz, Svetlana Hetjens, Christiane Otto, Michael Boettcher, Thomas Schaible and Neysan Rafat"]},"recId":"187638493X","person":[{"role":"aut","family":"Wegele","display":"Wegele, Christian","given":"Christian"},{"display":"Schreiner, Yannick","given":"Yannick","family":"Schreiner","role":"aut"},{"role":"aut","display":"Perez Ortiz, Alba","given":"Alba","family":"Perez Ortiz"},{"display":"Hetjens, Svetlana","given":"Svetlana","family":"Hetjens","role":"aut"},{"given":"Christiane","display":"Otto, Christiane","family":"Otto","role":"aut"},{"given":"Michael","display":"Boettcher, Michael","family":"Boettcher","role":"aut"},{"family":"Schaible","display":"Schaible, Thomas","given":"Thomas","role":"aut"},{"role":"aut","family":"Rafat","given":"Neysan","display":"Rafat, Neysan"}],"note":["Dieser Artikel gehört zum Special issue: Pediatric intensive care – practice and research)","Gesehen am 19.12.2023"],"relHost":[{"title":[{"title":"Children","title_sort":"Children","subtitle":"open access pediatrics journal"}],"language":["eng"],"origin":[{"dateIssuedKey":"2013","publisherPlace":"Basel","publisher":"MDPI","dateIssuedDisp":"2013-"}],"disp":"Impact of time point of extracorporeal membrane oxygenation on mortality and morbidity in congenital diaphragmatic hernia a single-center case seriesChildren","recId":"768093007","physDesc":[{"extent":"Online-Ressource"}],"id":{"eki":["768093007"],"zdb":["2732685-8"],"issn":["2227-9067"]},"pubHistory":["1.2013 -"],"part":{"extent":"8","issue":"7","year":"2022","pages":"1-8","text":"9(2022), 7, Artikel-ID 986, Seite 1-8","volume":"9"},"type":{"bibl":"periodical","media":"Online-Ressource"}}],"id":{"doi":["10.3390/children9070986"],"eki":["187638493X"]},"type":{"media":"Online-Ressource","bibl":"article-journal"},"physDesc":[{"extent":"8 S."}]} 
SRT |a WEGELECHRIIMPACTOFTI1202