Early carotid endarterectomy after non-disabling ischaemic stroke: adequate therapeutical option in selected patients

Objective: - To evaluate neurological outcome and long-term results of early carotid endarterectomy (CEA) after nondisabling stroke. - Materials: - Retrospective study between 1980 and 1995 of 56 patients undergoing CEA within 4 weeks of a transient (n = 15) or a permanent non-disabling (n = 41) isc...

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Main Authors: Eckstein, Hans-Henning (Author) , Schumacher, Hardy (Author) , Laubach, Hans-Heinrich (Author) , Ringleb, Peter A. (Author) , Forsting, Michael (Author) , Dörfler, Arnd (Author) , Bardenheuer, Hubert J. (Author) , Allenberg, Jens-Rainer (Author)
Format: Article (Journal)
Language:English
Published: 1998
In: European journal of vascular and endovascular surgery
Year: 1998, Volume: 15, Issue: 5, Pages: 423-428
ISSN:1532-2165
DOI:10.1016/S1078-5884(98)80204-9
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S1078-5884(98)80204-9
Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1078588498802049
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Author Notes:H.-H. Eckstein, H. Schumacher, H. Laubach, P. Ringleb, M. Forsting, A. Dörfler, H. Bardenheuer, J.-R. Allenberg

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520 |a Objective: - To evaluate neurological outcome and long-term results of early carotid endarterectomy (CEA) after nondisabling stroke. - Materials: - Retrospective study between 1980 and 1995 of 56 patients undergoing CEA within 4 weeks of a transient (n = 15) or a permanent non-disabling (n = 41) ischaemic stroke. - Methods: - Analyses of preoperative cerebral CT imaging, neurological outcome (mod. Rankin-scale) and long-term results (life-table analyses according to Kaplan-Meier). - Results: - Incidence of early CEA increased from 1.7% (27 out of 1636) in the period 1980-1993 to 7.8% (29 out of 374) between 1994 and 1995. CEA was indicated after a neurological plateau phase was established (median interval 14 days). Fifty-seven per cent of the CEA patients had a minor ischaemic infarction (area <2 cm), 18% showed a large territorial ischaemic infarction (area 2-5 cm) in cerebral CT imaging. Two patients deteriorated postoperatively (minor stroke rate 4%) but no major stroke or death occurred. Life-table probability of stroke-free survival (mean follow-up 42.7 months) was 94%, 90% and 84%, respectively, after 1, 2 and 5 years. Kaplan-Meier survival rates were 96%, 91% and 86% after 1, 2 and 5 years: - Conclusions: - Early CEA after non-disabling stroke is a safe procedure in selected patients. 
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