High recurrence rate of eczema herpeticum in moderate/severe atopic dermatitis: TREATGermany registry analysis
Background Eczema herpeticum (EH) is a disseminated skin infection caused by herpes simplex virus in atopic dermatitis (AD) patients. The frequency of EH and the clinical features of EH patients have not yet been investigated in a larger cohort. Methods We sought to investigate the TREATgermany coho...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
09 October 2023
|
| In: |
Journal der Deutschen Dermatologischen Gesellschaft
Year: 2023, Jahrgang: 21, Heft: 12, Pages: 1490-1498 |
| ISSN: | 1610-0387 |
| DOI: | 10.1111/ddg.15205 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1111/ddg.15205 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/ddg.15205 
|
| Verfasserangaben: | Stephan Traidl, Luise Heinrich, Doreen Siegels, Lennart Rösner, Eva Haufe, Inken Harder, Susanne Abraham, Konstantin Ertner, Andreas Kleinheinz, Knut Schäkel, Andreas Wollenberg, Isaak Effendy, Sven Quist, Andrea Asmussen, Julia Wildberger, Elke Weisshaar, Franka Wiemers, Jens-Joachim Brücher, Stephan Weidinger, Jochen Schmitt, Thomas Werfel, the TREATgermany Study Group |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1877496812 | ||
| 003 | DE-627 | ||
| 005 | 20240307031458.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240109s2023 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/ddg.15205 |2 doi | |
| 035 | |a (DE-627)1877496812 | ||
| 035 | |a (DE-599)KXP1877496812 | ||
| 035 | |a (OCoLC)1425207920 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Traidl, Stephan |d 1993- |e VerfasserIn |0 (DE-588)1183620160 |0 (DE-627)1663247250 |4 aut | |
| 245 | 1 | 0 | |a High recurrence rate of eczema herpeticum in moderate/severe atopic dermatitis |b TREATGermany registry analysis |c Stephan Traidl, Luise Heinrich, Doreen Siegels, Lennart Rösner, Eva Haufe, Inken Harder, Susanne Abraham, Konstantin Ertner, Andreas Kleinheinz, Knut Schäkel, Andreas Wollenberg, Isaak Effendy, Sven Quist, Andrea Asmussen, Julia Wildberger, Elke Weisshaar, Franka Wiemers, Jens-Joachim Brücher, Stephan Weidinger, Jochen Schmitt, Thomas Werfel, the TREATgermany Study Group |
| 264 | 1 | |c 09 October 2023 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 09.01.2024 | ||
| 520 | |a Background Eczema herpeticum (EH) is a disseminated skin infection caused by herpes simplex virus in atopic dermatitis (AD) patients. The frequency of EH and the clinical features of EH patients have not yet been investigated in a larger cohort. Methods We sought to investigate the TREATgermany cohort, a multicenter, non-interventional clinical registry of moderately to severely affected AD patients in Germany. Baseline characteristics of patients included between December 2017 and April 2021 were compared between patients without, single, and multiple EH. Results Of the 893 patients, 195 (21.8%) had at least one EH. Of the 195 patients with EH, 107 had multiple EH (54.9%), representing 12.0% of the total study population. While there were no differences in demographic characteristics, previous treatment, and disease scores at enrollment (itch, IGA, oSCORAD, EASI), patients with EH had more frequent atopic comorbidities and sensitizations to house dust mite, food, and mold. Discussion TREATgermany registry data suggest a high prevalence and recurrence rate of EH, while there appears to be no specific clinical phenotype, besides an increase in allergies, to identify EH patients in the daily routine. | ||
| 650 | 4 | |a Atopic dermatitis | |
| 650 | 4 | |a herpes simplex | |
| 650 | 4 | |a registry | |
| 700 | 1 | |a Heinrich, Luise |e VerfasserIn |4 aut | |
| 700 | 1 | |a Siegels, Doreen |e VerfasserIn |4 aut | |
| 700 | 1 | |a Rösner, Lennart |e VerfasserIn |4 aut | |
| 700 | 1 | |a Haufe, Eva |e VerfasserIn |4 aut | |
| 700 | 1 | |a Harder, Inken |e VerfasserIn |4 aut | |
| 700 | 1 | |a Abraham, Susanne |e VerfasserIn |4 aut | |
| 700 | 1 | |a Ertner, Konstantin |e VerfasserIn |4 aut | |
| 700 | 1 | |a Kleinheinz, Andreas |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schäkel, Knut |e VerfasserIn |0 (DE-588)1032757418 |0 (DE-627)739272896 |0 (DE-576)251064476 |4 aut | |
| 700 | 1 | |a Wollenberg, Andreas |e VerfasserIn |4 aut | |
| 700 | 1 | |a Effendy, Isaak |e VerfasserIn |4 aut | |
| 700 | 1 | |a Quist, Sven |e VerfasserIn |4 aut | |
| 700 | 1 | |a Asmussen, Andrea |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wildberger, Julia |e VerfasserIn |4 aut | |
| 700 | 1 | |a Weisshaar, Elke |e VerfasserIn |0 (DE-588)1032807369 |0 (DE-627)739344870 |0 (DE-576)271388579 |4 aut | |
| 700 | 1 | |a Wiemers, Franka |e VerfasserIn |4 aut | |
| 700 | 1 | |a Brücher, Jens-Joachim |e VerfasserIn |4 aut | |
| 700 | 1 | |a Weidinger, Stephan |e VerfasserIn |4 aut | |
| 700 | 1 | |a Schmitt, Jochen |e VerfasserIn |4 aut | |
| 700 | 1 | |a Werfel, Thomas |d 1959- |e VerfasserIn |0 (DE-588)132092751 |0 (DE-627)517557843 |0 (DE-576)186874316 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |a Deutsche Dermatologische Gesellschaft |t Journal der Deutschen Dermatologischen Gesellschaft |d Berlin : Wiley-Blackwell, 2003 |g 21(2023), 12, Seite 1490-1498 |h Online-Ressource |w (DE-627)362755833 |w (DE-600)2099463-1 |w (DE-576)103373837 |x 1610-0387 |7 nnas |
| 773 | 1 | 8 | |g volume:21 |g year:2023 |g number:12 |g pages:1490-1498 |g extent:9 |a High recurrence rate of eczema herpeticum in moderate/severe atopic dermatitis TREATGermany registry analysis |
| 856 | 4 | 0 | |u https://doi.org/10.1111/ddg.15205 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1111/ddg.15205 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20240109 | ||
| 993 | |a Article | ||
| 994 | |a 2023 | ||
| 998 | |g 1032807369 |a Weisshaar, Elke |m 1032807369:Weisshaar, Elke |d 910000 |d 911300 |d 50000 |e 910000PW1032807369 |e 911300PW1032807369 |e 50000PW1032807369 |k 0/910000/ |k 1/910000/911300/ |k 0/50000/ |p 2 | ||
| 998 | |g 1032757418 |a Schäkel, Knut |m 1032757418:Schäkel, Knut |d 910000 |d 911300 |e 910000PS1032757418 |e 911300PS1032757418 |k 0/910000/ |k 1/910000/911300/ |p 10 | ||
| 999 | |a KXP-PPN1877496812 |e 4451584183 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"name":{"displayForm":["Stephan Traidl, Luise Heinrich, Doreen Siegels, Lennart Rösner, Eva Haufe, Inken Harder, Susanne Abraham, Konstantin Ertner, Andreas Kleinheinz, Knut Schäkel, Andreas Wollenberg, Isaak Effendy, Sven Quist, Andrea Asmussen, Julia Wildberger, Elke Weisshaar, Franka Wiemers, Jens-Joachim Brücher, Stephan Weidinger, Jochen Schmitt, Thomas Werfel, the TREATgermany Study Group"]},"note":["Gesehen am 09.01.2024"],"recId":"1877496812","id":{"doi":["10.1111/ddg.15205"],"eki":["1877496812"]},"language":["eng"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"origin":[{"dateIssuedKey":"2023","dateIssuedDisp":"09 October 2023"}],"physDesc":[{"extent":"9 S."}],"person":[{"role":"aut","family":"Traidl","display":"Traidl, Stephan","given":"Stephan"},{"family":"Heinrich","display":"Heinrich, Luise","given":"Luise","role":"aut"},{"role":"aut","family":"Siegels","display":"Siegels, Doreen","given":"Doreen"},{"role":"aut","family":"Rösner","display":"Rösner, Lennart","given":"Lennart"},{"role":"aut","given":"Eva","family":"Haufe","display":"Haufe, Eva"},{"role":"aut","family":"Harder","display":"Harder, Inken","given":"Inken"},{"role":"aut","display":"Abraham, Susanne","family":"Abraham","given":"Susanne"},{"role":"aut","given":"Konstantin","display":"Ertner, Konstantin","family":"Ertner"},{"family":"Kleinheinz","display":"Kleinheinz, Andreas","given":"Andreas","role":"aut"},{"role":"aut","display":"Schäkel, Knut","family":"Schäkel","given":"Knut"},{"role":"aut","display":"Wollenberg, Andreas","family":"Wollenberg","given":"Andreas"},{"role":"aut","given":"Isaak","display":"Effendy, Isaak","family":"Effendy"},{"given":"Sven","family":"Quist","display":"Quist, Sven","role":"aut"},{"role":"aut","given":"Andrea","family":"Asmussen","display":"Asmussen, Andrea"},{"role":"aut","family":"Wildberger","display":"Wildberger, Julia","given":"Julia"},{"given":"Elke","family":"Weisshaar","display":"Weisshaar, Elke","role":"aut"},{"given":"Franka","display":"Wiemers, Franka","family":"Wiemers","role":"aut"},{"role":"aut","given":"Jens-Joachim","display":"Brücher, Jens-Joachim","family":"Brücher"},{"family":"Weidinger","display":"Weidinger, Stephan","given":"Stephan","role":"aut"},{"given":"Jochen","display":"Schmitt, Jochen","family":"Schmitt","role":"aut"},{"given":"Thomas","display":"Werfel, Thomas","family":"Werfel","role":"aut"}],"title":[{"title_sort":"High recurrence rate of eczema herpeticum in moderate/severe atopic dermatitis","subtitle":"TREATGermany registry analysis","title":"High recurrence rate of eczema herpeticum in moderate/severe atopic dermatitis"}],"relHost":[{"origin":[{"publisherPlace":"Berlin ; Berlin","dateIssuedDisp":"2003-","dateIssuedKey":"2003","publisher":"Wiley-Blackwell ; Blackwell"}],"titleTranslated":[{"translated":"Journal of the German Society of Dermatology"}],"physDesc":[{"extent":"Online-Ressource"}],"titleAlt":[{"title":"JDDG"}],"title":[{"title_sort":"Journal der Deutschen Dermatologischen Gesellschaft","subtitle":"JDDG = Journal of the German Society of Dermatology","title":"Journal der Deutschen Dermatologischen Gesellschaft"}],"part":{"volume":"21","text":"21(2023), 12, Seite 1490-1498","pages":"1490-1498","extent":"9","year":"2023","issue":"12"},"disp":"Deutsche Dermatologische GesellschaftJournal der Deutschen Dermatologischen Gesellschaft","pubHistory":["1.2003 -"],"note":["Gesehen am 03.03.10"],"recId":"362755833","id":{"eki":["362755833"],"doi":["10.1111/(ISSN)1610-0387"],"zdb":["2099463-1"],"issn":["1610-0387"]},"corporate":[{"display":"Deutsche Dermatologische Gesellschaft","role":"aut"}],"language":["ger","eng"],"type":{"bibl":"periodical","media":"Online-Ressource"}}]} | ||
| SRT | |a TRAIDLSTEPHIGHRECURR0920 | ||