RAG mutations in human B cell-negative SCID

Patients with human severe combined immunodeficiency (SCID) can be divided into those with B lymphocytes (B+ SCID) and those without (B− SCID). Although several genetic causes are known for B+ SCID, the etiology of B− SCID has not been defined. Six of 14 B− SCID patients tested were found to carry a...

Full description

Bibliographic Details

Main Authors:	Schwarz, Klaus (Author) , Gauss, George H. (Author) , Ludwig, Leopold (Author) , Pannicke, Ulrich (Author) , Li, Zhong (Author) , Lindner, Doris (Author) , Friedrich, Wilhelm (Author) , Seger, Reinhard A. (Author) , Hansen-Hagge, Thomas E. (Author) , Desiderio, Stephen (Author) , Lieber, Michael R. (Author) , Bartram, Claus R. (Author)
Format:	Article (Journal)
Language:	English
Published:	4 Oct 1996
In:	Science Year: 1996, Volume: 274, Issue: 5284, Pages: 97-99
ISSN:	1095-9203
DOI:	10.1126/science.274.5284.97
Online Access:	Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1126/science.274.5284.97 Verlag, lizenzpflichtig, Volltext: https://www.science.org/doi/10.1126/science.274.5284.97
Author Notes:	Klaus Schwarz, George H. Gauss, Leopold Ludwig, Ulrich Pannicke, Zhong Li, Doris Lindner, Wilhelm Friedrich, Reinhard A. Seger, Thomas E. Hansen-Hagge, Stephen Desiderio, Michael R. Lieber, Claus R. Bartram