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Lung diffusing capacity and exercise in subjects with previous high altitude pulmonary oedema

Subjects with a history of high-altitude pulmonary oedema (HAPE) have increased pulmonary artery pressure and more ventilation-perfusion (V 'A/Q ') inhomogeneity with hypoxia and exercise. We used noninvasive methods to determine whether there are differences in the pulmonary diffusing cap...

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Main Authors: Steinacker, Jürgen M. (Author) , Tobias, P. (Author) , Menold, E. (Author) , Reissnecker, S. (Author) , Hohenhaus, Elke (Author) , Liu, Y. (Author) , Lehmann, M. (Author) , Bärtsch, Peter (Author) , Swenson, Erik R. (Author)
Format: Article (Journal)
Language:English
Published: 1998
In: The European respiratory journal
Year: 1998, Volume: 11, Issue: 3, Pages: 643-650
ISSN:1399-3003
DOI:10.1183/09031936.98.11030643
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1183/09031936.98.11030643
Verlag, lizenzpflichtig, Volltext: http://erj.ersjournals.com/lookup/doi/10.1183/09031936.98.11030643
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Author Notes:Jm Steinacker, P Tobias, E Menold, S Reissnecker, E Hohenhaus, Y Liu, M Lehmann, P Bartsch, Er Swenson

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520 |a Subjects with a history of high-altitude pulmonary oedema (HAPE) have increased pulmonary artery pressure and more ventilation-perfusion (V 'A/Q ') inhomogeneity with hypoxia and exercise. We used noninvasive methods to determine whether there are differences in the pulmonary diffusing capacity for carbon monoxide (DL,CO) and cardiac output (Q ') during exercise, indicative of a more restricted pulmonary vascular bed in subjects with a history of HAPE. 
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