Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels
This study introduces a straightforward method for manufacturing 3D microstructured cell-adhesive and cell-repellent multimaterials using two-photon laser printing. Compared to existing strategies, this approach offers bottom-up molecular control, high customizability and rapid and precise 3D fabric...
Gespeichert in:
| Hauptverfasser: | , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) Kapitel/Artikel |
| Sprache: | Englisch |
| Veröffentlicht: |
17 January 2024
|
| Ausgabe: | Version 1 |
| In: |
ChemRxiv
Year: 2024, Pages: 1-13 |
| DOI: | 10.26434/chemrxiv-2024-f94sf |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.26434/chemrxiv-2024-f94sf Verlag, lizenzpflichtig, Volltext: https://chemrxiv.org/engage/chemrxiv/article-details/65a63933e9ebbb4db943fa99 
|
| Verfasserangaben: | Niklas Schwegler, Tanisha Gebert, Maria Villiou, Federico Colombo, Barbara Schamberger, Christine Selhuber-Unkel, Franziska Thomas, and Eva Blasco |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1881333272 | ||
| 003 | DE-627 | ||
| 005 | 20240307020214.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240221s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.26434/chemrxiv-2024-f94sf |2 doi | |
| 035 | |a (DE-627)1881333272 | ||
| 035 | |a (DE-599)KXP1881333272 | ||
| 035 | |a (OCoLC)1425200166 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 30 |2 sdnb | ||
| 100 | 1 | |a Schwegler, Niklas |d 1998- |e VerfasserIn |0 (DE-588)1321204558 |0 (DE-627)1881329895 |4 aut | |
| 245 | 1 | 0 | |a Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels |c Niklas Schwegler, Tanisha Gebert, Maria Villiou, Federico Colombo, Barbara Schamberger, Christine Selhuber-Unkel, Franziska Thomas, and Eva Blasco |
| 250 | |a Version 1 | ||
| 264 | 1 | |c 17 January 2024 | |
| 300 | |a 13 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 21.02.2024 | ||
| 520 | |a This study introduces a straightforward method for manufacturing 3D microstructured cell-adhesive and cell-repellent multimaterials using two-photon laser printing. Compared to existing strategies, this approach offers bottom-up molecular control, high customizability and rapid and precise 3D fabrication. The printable cell-adhesive PEG-based material includes an RGD-containing peptide synthesized through solid-phase peptide synthesis, allowing for precise control of the peptide design. Remarkably, minimal amounts of RGD peptide (< 0.1 wt%) suffice for imparting cell-adhesiveness, while maintaining identical mechanical properties in the 3D printed microstructures to those of the cell-repellent, PEG-based material. Fluorescent labeling of the RGD peptide facilitates visualization of its presence in cell-adhesive areas. To demonstrate the broad applicability of our system, we showcase the fabrication of cell-adhesive 2.5D and 3D structures, fostering the adhesion of fibroblast cells within these architectures. Thus, this approach allows for the printing of high-resolution, true 3D structures suitable for diverse applications, including cellular studies in complex environments. | ||
| 650 | 4 | |a cell adhesion | |
| 650 | 4 | |a direct laser writing | |
| 650 | 4 | |a hydrogels | |
| 650 | 4 | |a RGD | |
| 650 | 4 | |a two-photon | |
| 700 | 1 | |a Gebert, Tanisha |d 1995- |e VerfasserIn |0 (DE-588)1321204744 |0 (DE-627)1881330583 |4 aut | |
| 700 | 1 | |a Villiou, Maria |d 1992- |e VerfasserIn |0 (DE-588)1321204868 |0 (DE-627)1881330877 |4 aut | |
| 700 | 1 | |a Colombo, Federico |d 1988- |e VerfasserIn |0 (DE-588)1280334428 |0 (DE-627)1833427920 |4 aut | |
| 700 | 1 | |a Schamberger, Barbara |d 1992- |e VerfasserIn |0 (DE-588)1321177445 |0 (DE-627)1881313565 |4 aut | |
| 700 | 1 | |a Selhuber-Unkel, Christine |d 1980- |e VerfasserIn |0 (DE-588)132414759 |0 (DE-627)522682626 |0 (DE-576)299131491 |4 aut | |
| 700 | 1 | |a Thomas, Franziska |d 1980- |e VerfasserIn |0 (DE-588)142471976 |0 (DE-627)704236850 |0 (DE-576)330898442 |4 aut | |
| 700 | 1 | |a Blasco, Eva |e VerfasserIn |0 (DE-588)1226861067 |0 (DE-627)1747963801 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t ChemRxiv |d [Washington, DC] : American Chemical Society (ACS), 2018 |g (2024) vom: 17. Jan., Seite 1-13 |h Online-Ressource |w (DE-627)1040473423 |w (DE-600)2949094-7 |w (DE-576)513680780 |7 nnas |a Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels |
| 773 | 1 | 8 | |g year:2024 |g day:17 |g month:01 |g pages:1-13 |g extent:13 |a Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels |
| 787 | 0 | 8 | |i Forschungsdaten |a Schwegler, Niklas, 1998 - |t Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels [data] |d Heidelberg : Universität, 2024 |h 1 Online-Ressource (2 Files) |w (DE-627)1881329143 |
| 856 | 4 | 0 | |u https://doi.org/10.26434/chemrxiv-2024-f94sf |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://chemrxiv.org/engage/chemrxiv/article-details/65a63933e9ebbb4db943fa99 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20240221 | ||
| 993 | |a Article | ||
| 994 | |a 2024 | ||
| 998 | |g 1226861067 |a Blasco, Eva |m 1226861067:Blasco, Eva |d 160000 |d 160200 |e 160000PB1226861067 |e 160200PB1226861067 |k 0/160000/ |k 1/160000/160200/ |p 8 |y j | ||
| 998 | |g 142471976 |a Thomas, Franziska |m 142471976:Thomas, Franziska |d 120000 |d 120100 |e 120000PT142471976 |e 120100PT142471976 |k 0/120000/ |k 1/120000/120100/ |p 7 | ||
| 998 | |g 132414759 |a Selhuber-Unkel, Christine |m 132414759:Selhuber-Unkel, Christine |d 160000 |d 160200 |e 160000PS132414759 |e 160200PS132414759 |k 0/160000/ |k 1/160000/160200/ |p 6 | ||
| 998 | |g 1321177445 |a Schamberger, Barbara |m 1321177445:Schamberger, Barbara |d 160000 |d 160200 |e 160000PS1321177445 |e 160200PS1321177445 |k 0/160000/ |k 1/160000/160200/ |p 5 | ||
| 998 | |g 1280334428 |a Colombo, Federico |m 1280334428:Colombo, Federico |d 160000 |d 160200 |e 160000PC1280334428 |e 160200PC1280334428 |k 0/160000/ |k 1/160000/160200/ |p 4 | ||
| 998 | |g 1321204868 |a Villiou, Maria |m 1321204868:Villiou, Maria |d 120000 |e 120000PV1321204868 |k 0/120000/ |p 3 | ||
| 998 | |g 1321204744 |a Gebert, Tanisha |m 1321204744:Gebert, Tanisha |d 160000 |d 160200 |e 160000PG1321204744 |e 160200PG1321204744 |k 0/160000/ |k 1/160000/160200/ |p 2 | ||
| 998 | |g 1321204558 |a Schwegler, Niklas |m 1321204558:Schwegler, Niklas |d 160000 |d 160200 |e 160000PS1321204558 |e 160200PS1321204558 |k 0/160000/ |k 1/160000/160200/ |p 1 |x j | ||
| 999 | |a KXP-PPN1881333272 |e 4489442521 | ||
| BIB | |a Y | ||
| JSO | |a {"id":{"doi":["10.26434/chemrxiv-2024-f94sf"],"eki":["1881333272"]},"name":{"displayForm":["Niklas Schwegler, Tanisha Gebert, Maria Villiou, Federico Colombo, Barbara Schamberger, Christine Selhuber-Unkel, Franziska Thomas, and Eva Blasco"]},"type":{"media":"Online-Ressource","bibl":"chapter"},"language":["eng"],"note":["Gesehen am 21.02.2024"],"title":[{"title_sort":"Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels","title":"Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogels"}],"origin":[{"edition":"Version 1","dateIssuedKey":"2024","dateIssuedDisp":"17 January 2024"}],"person":[{"display":"Schwegler, Niklas","given":"Niklas","role":"aut","family":"Schwegler"},{"family":"Gebert","role":"aut","given":"Tanisha","display":"Gebert, Tanisha"},{"display":"Villiou, Maria","family":"Villiou","role":"aut","given":"Maria"},{"role":"aut","given":"Federico","family":"Colombo","display":"Colombo, Federico"},{"family":"Schamberger","role":"aut","given":"Barbara","display":"Schamberger, Barbara"},{"role":"aut","given":"Christine","family":"Selhuber-Unkel","display":"Selhuber-Unkel, Christine"},{"family":"Thomas","role":"aut","given":"Franziska","display":"Thomas, Franziska"},{"given":"Eva","role":"aut","family":"Blasco","display":"Blasco, Eva"}],"relHost":[{"part":{"year":"2024","pages":"1-13","extent":"13","text":"(2024) vom: 17. Jan., Seite 1-13"},"id":{"eki":["1040473423"],"zdb":["2949094-7"]},"name":{"displayForm":["ACS, GDCh, Royal Society of Chemistry"]},"corporate":[{"role":"isb","display":"American Chemical Society"},{"role":"isb","display":"Gesellschaft Deutscher Chemiker"},{"role":"isb","display":"Royal Society of Chemistry"}],"disp":"Multimaterial 3D laser printing of cell-adhesive and cell-repellent hydrogelsChemRxiv","recId":"1040473423","physDesc":[{"extent":"Online-Ressource"}],"title":[{"subtitle":"the Preprint Server for Chemistry","title":"ChemRxiv","title_sort":"ChemRxiv"}],"note":["Gesehen am 13.11.18"],"language":["eng"],"type":{"media":"Online-Ressource","bibl":"edited-book"},"origin":[{"publisher":"American Chemical Society (ACS) ; German Chemical Society (GDCh) ; Royal Society of Chemistry","dateIssuedDisp":"2018-","dateIssuedKey":"2018","publisherPlace":"[Washington, DC] ; [Frankfurt am Main] ; [Cambridge ; London]"}]}],"physDesc":[{"extent":"13 S."}],"recId":"1881333272"} | ||
| SRT | |a SCHWEGLERNMULTIMATER1720 | ||