Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson
Spondias dulcis Parkinson have been used in traditional medicine in Asia, Oceania, and South America, for different diseases conditions and as a functional food. The scientific literature described as different potential pharmacology such as antioxidant, anti-inflammatory, antimicrobial, thrombolyti...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2024
|
| In: |
Natural product research
Year: 2024, Jahrgang: 38, Heft: 6, Pages: 1049-1053 |
| ISSN: | 1478-6427 |
| DOI: | 10.1080/14786419.2023.2210254 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1080/14786419.2023.2210254 Verlag, lizenzpflichtig, Volltext: https://www.tandfonline.com/doi/full/10.1080/14786419.2023.2210254 
|
| Verfasserangaben: | Felipe Hugo Alencar Fernandes, Sabrina da Silva Soares, Elmira Bekbolatova, Fábio Boylan, Hérida Regina Nunes Salgado |
MARC
| LEADER | 00000caa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1882042646 | ||
| 003 | DE-627 | ||
| 005 | 20240307015649.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240228s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1080/14786419.2023.2210254 |2 doi | |
| 035 | |a (DE-627)1882042646 | ||
| 035 | |a (DE-599)KXP1882042646 | ||
| 035 | |a (OCoLC)1425200100 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Alencar Fernandes, Felipe Hugo |e VerfasserIn |0 (DE-588)1321897286 |0 (DE-627)1882043723 |4 aut | |
| 245 | 1 | 0 | |a Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson |c Felipe Hugo Alencar Fernandes, Sabrina da Silva Soares, Elmira Bekbolatova, Fábio Boylan, Hérida Regina Nunes Salgado |
| 264 | 1 | |c 2024 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online veröffentlicht: 8. Mai 2023 | ||
| 500 | |a Gesehen am 28.02.2024 | ||
| 520 | |a Spondias dulcis Parkinson have been used in traditional medicine in Asia, Oceania, and South America, for different diseases conditions and as a functional food. The scientific literature described as different potential pharmacology such as antioxidant, anti-inflammatory, antimicrobial, thrombolytic and enzymatic inhibitor. This study aimed to: (1) establish the pharmacological activity in intestinal motility in vivo and antioxidant activity in vitro; (2) perform the acute toxicology test in mouse; (3) characterize the phytochemical profile based on counter-current chromatography (CCC) and NMR analysis. The results revealed a laxative effect of S. dulcis extract and a high antioxidant activity (IC50 = 5.10 for DPPH assay and 14.14 for hydrogen peroxide scavenging test). No side effects were observed in the oral acute toxicity test for a dose up to 2000 mg/kg. The chemical profile was identified by CCC and NMR, and the comparison of the data obtained with previous literature revealed the presence of the flavonoid rutin (Quercetin-3-O-rutinoside) in the extract. | ||
| 650 | 4 | |a antioxidant activity | |
| 650 | 4 | |a countercurrent chromatography | |
| 650 | 4 | |a Laxative activity | |
| 650 | 4 | |a rutin | |
| 700 | 1 | |a Soares, Sabrina |d 1984- |e VerfasserIn |0 (DE-588)1228107106 |0 (DE-627)1749401614 |4 aut | |
| 700 | 1 | |a Bekbolatova, Elmira |e VerfasserIn |4 aut | |
| 700 | 1 | |a Boylan, Fábio |e VerfasserIn |4 aut | |
| 700 | 1 | |a Salgado, Hérida Regina Nunes |e VerfasserIn |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Natural product research |d London [u.a.] : Taylor & Francis, 2003 |g 38(2024), 6, Seite 1049-1053 |h Online-Ressource |w (DE-627)484658565 |w (DE-600)2185747-7 |w (DE-576)275076989 |x 1478-6427 |7 nnas |a Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson |
| 773 | 1 | 8 | |g volume:38 |g year:2024 |g number:6 |g pages:1049-1053 |g extent:5 |a Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson |
| 856 | 4 | 0 | |u https://doi.org/10.1080/14786419.2023.2210254 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://www.tandfonline.com/doi/full/10.1080/14786419.2023.2210254 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20240228 | ||
| 993 | |a Article | ||
| 994 | |a 2024 | ||
| 998 | |g 1228107106 |a Soares, Sabrina |m 1228107106:Soares, Sabrina |d 60000 |e 60000PS1228107106 |k 0/60000/ |p 2 | ||
| 999 | |a KXP-PPN1882042646 |e 4493013575 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Online veröffentlicht: 8. Mai 2023","Gesehen am 28.02.2024"],"person":[{"role":"aut","family":"Alencar Fernandes","given":"Felipe Hugo","display":"Alencar Fernandes, Felipe Hugo"},{"role":"aut","given":"Sabrina","family":"Soares","display":"Soares, Sabrina"},{"family":"Bekbolatova","given":"Elmira","display":"Bekbolatova, Elmira","role":"aut"},{"role":"aut","display":"Boylan, Fábio","family":"Boylan","given":"Fábio"},{"role":"aut","given":"Hérida Regina Nunes","family":"Salgado","display":"Salgado, Hérida Regina Nunes"}],"title":[{"title_sort":"Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson","title":"Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinson"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"origin":[{"dateIssuedKey":"2024","dateIssuedDisp":"2024"}],"physDesc":[{"extent":"5 S."}],"language":["eng"],"recId":"1882042646","id":{"doi":["10.1080/14786419.2023.2210254"],"eki":["1882042646"]},"name":{"displayForm":["Felipe Hugo Alencar Fernandes, Sabrina da Silva Soares, Elmira Bekbolatova, Fábio Boylan, Hérida Regina Nunes Salgado"]},"relHost":[{"type":{"bibl":"periodical","media":"Online-Ressource"},"origin":[{"dateIssuedDisp":"2003-","publisherPlace":"London [u.a.]","publisher":"Taylor & Francis","dateIssuedKey":"2003"}],"pubHistory":["17.2003 -"],"title":[{"title_sort":"Natural product research","title":"Natural product research"}],"note":["Gesehen am 03.04.2023"],"recId":"484658565","id":{"zdb":["2185747-7"],"issn":["1478-6427"],"eki":["484658565"]},"language":["eng"],"part":{"extent":"5","pages":"1049-1053","volume":"38","text":"38(2024), 6, Seite 1049-1053","issue":"6","year":"2024"},"disp":"Pharmacological, toxicological and phytochemical analysis of Spondias dulcis parkinsonNatural product research","physDesc":[{"extent":"Online-Ressource"}]}]} | ||
| SRT | |a ALENCARFERPHARMACOLO2024 | ||