Influence of a short course of ritonavir used as booster in antiviral therapies against SARS-CoV-2 on the exposure of atorvastatin and rosuvastatin
Early antiviral treatment with nirmatrelvir/ritonavir is recommended for SARS-CoV-2-infected patients at high risk for severe courses. Such patients are usually chronically ill and susceptible to adverse drug interactions caused by ritonavir. We investigated the interactions of short-term low-dose r...
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| Hauptverfasser: | , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2025
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| In: |
Cardiovascular drugs and therapy
Year: 2025, Jahrgang: 39, Pages: 325–335 |
| ISSN: | 1573-7241 |
| DOI: | 10.1007/s10557-023-07538-w |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s10557-023-07538-w Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s10557-023-07538-w 
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| Verfasserangaben: | Evelyn Krohmer, Brit Silja Rohr, Felicitas Stoll, Katja S. Gümüs, Mariano Bergamino, Gerd Mikus, Max Sauter, Jürgen Burhenne, Johanna Weiss, Andreas D. Meid, David Czock, Antje Blank, Walter E. Haefeli |
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| 520 | |a Early antiviral treatment with nirmatrelvir/ritonavir is recommended for SARS-CoV-2-infected patients at high risk for severe courses. Such patients are usually chronically ill and susceptible to adverse drug interactions caused by ritonavir. We investigated the interactions of short-term low-dose ritonavir therapy with atorvastatin and rosuvastatin, two statins commonly used in this population. | ||
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