Venlafaxine’s therapeutic reference range in the treatment of depression revised: a systematic review and meta-analysis: original investigation
The selective serotonin and norepinephrine reuptake inhibitor venlafaxine is among the most prescribed antidepressant drugs worldwide and, according to guidelines, its dose titration should be guided by drug-level monitoring of its active moiety (AM) which consists of venlafaxine (VEN) plus active m...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
February 2024
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| In: |
Psychopharmacology
Year: 2024, Jahrgang: 241, Heft: 2, Pages: 275-289 |
| ISSN: | 1432-2072 |
| DOI: | 10.1007/s00213-023-06484-7 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00213-023-06484-7 Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00213-023-06484-7 
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| Verfasserangaben: | X.M. Lense, C. Hiemke, C.S.M. Funk, U. Havemann-Reinecke, G. Hefner, A. Menke, R. Mössner, T.G. Riemer, M. Scherf-Clavel, G. Schoretsanitis, G. Gründer, X.M. Hart |
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| 520 | |a The selective serotonin and norepinephrine reuptake inhibitor venlafaxine is among the most prescribed antidepressant drugs worldwide and, according to guidelines, its dose titration should be guided by drug-level monitoring of its active moiety (AM) which consists of venlafaxine (VEN) plus active metabolite O-desmethylvenlafaxine (ODV). This indication of therapeutic drug monitoring (TDM), however, assumes a clear concentration/effect relationship for a drug, which for VEN has not been systematically explored yet. | ||
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