Circulating oxysterols and prognosis among women with a breast cancer diagnosis: results from the MARIE patient cohort
Breast cancer is the most commonly diagnosed cancer in women worldwide, and underlying mechanistic pathways associated with breast cancer-specific and non-breast cancer-related deaths are of importance. Emerging evidence suggests a role of oxysterols, derivates of cholesterol, in multiple chronic di...
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| Hauptverfasser: | , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
14 November 2023
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| In: |
BMC medicine
Year: 2023, Jahrgang: 21, Heft: 1, Pages: 1-12 |
| ISSN: | 1741-7015 |
| DOI: | 10.1186/s12916-023-03152-7 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1186/s12916-023-03152-7
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| Verfasserangaben: | Nina Sophia Decker, Theron Johnson, Johannes A. Vey, Charlotte Le Cornet, Sabine Behrens, Nadia Obi, Rudolf Kaaks, Jenny Chang-Claude and Renée Turzanski Fortner |
MARC
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| 520 | |a Breast cancer is the most commonly diagnosed cancer in women worldwide, and underlying mechanistic pathways associated with breast cancer-specific and non-breast cancer-related deaths are of importance. Emerging evidence suggests a role of oxysterols, derivates of cholesterol, in multiple chronic diseases including breast cancer and coronary artery diseases. However, associations between oxysterols and survival have been minimally studied in women diagnosed with breast cancer. In this large breast cancer patient cohort, we evaluated associations between a panel of circulating oxysterols and mortality and recurrence outcomes. | ||
| 650 | 4 | |a Breast cancer | |
| 650 | 4 | |a Cancer death | |
| 650 | 4 | |a Cardiovascular death | |
| 650 | 4 | |a Cholesterol metabolism | |
| 650 | 4 | |a Cohort study | |
| 650 | 4 | |a Molecular epidemiology | |
| 650 | 4 | |a Oxysterols | |
| 650 | 4 | |a Survival | |
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