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Development of CAR T cell therapy in children: a comprehensive overview

CAR T cell therapy has revolutionized immunotherapy in the last decade with the successful establishment of chimeric antigen receptor (CAR)-expressing cellular therapies as an alternative treatment in relapsed and refractory CD19-positive leukemias and lymphomas. There are fundamental reasons why CA...

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Main Authors: Boettcher, Michael (Author) , Joechner, Alexander (Author) , Li, Ziduo (Author) , Yang, Sile Fiona (Author) , Schlegel, Patrick (Author)
Format: Article (Journal)
Language:English
Published: 12 April 2022
In: Journal of Clinical Medicine
Year: 2022, Volume: 11, Issue: 8, Pages: 1-43
ISSN:2077-0383
DOI:10.3390/jcm11082158
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/jcm11082158
Verlag, kostenfrei, Volltext: https://www.mdpi.com/2077-0383/11/8/2158
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Author Notes:Michael Boettcher, Alexander Joechner, Ziduo Li, Sile Fiona Yang and Patrick Schlegel

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