Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment: results from a prospective, randomized clinical trial
Aim Patients suffering from advanced colorectal cancer can experience unintended weight loss and/or treatment-induced gastrointestinal toxicity. Based on current evidence, the routine use of parenteral nutrition (PN) for patients with colorectal cancer is not recommended. This study evaluates the ef...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
October 2010
|
| In: |
Colorectal disease
Year: 2010, Jahrgang: 12, Heft: 10, Pages: e190-e199 |
| ISSN: | 1463-1318 |
| DOI: | 10.1111/j.1463-1318.2009.02111.x |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1111/j.1463-1318.2009.02111.x Verlag, lizenzpflichtig, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1463-1318.2009.02111.x 
|
| Verfasserangaben: | T. Hasenberg, M. Essenbreis, A. Herold, S. Post, E. Shang |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1883186072 | ||
| 003 | DE-627 | ||
| 005 | 20250818161109.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240312s2010 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1111/j.1463-1318.2009.02111.x |2 doi | |
| 035 | |a (DE-627)1883186072 | ||
| 035 | |a (DE-599)KXP1883186072 | ||
| 035 | |a (OCoLC)1443645460 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Hasenberg, Till |d 1974- |e VerfasserIn |0 (DE-588)124633315 |0 (DE-627)363458212 |0 (DE-576)186314477 |4 aut | |
| 245 | 1 | 0 | |a Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment |b results from a prospective, randomized clinical trial |c T. Hasenberg, M. Essenbreis, A. Herold, S. Post, E. Shang |
| 246 | 3 | 0 | |a zurückgezogen |
| 264 | 1 | |c October 2010 | |
| 300 | |a 10 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Der Artikel wurde zurückgezogen | ||
| 500 | |a First published: 06 November 2009 | ||
| 500 | |a Gesehen am 12.03.2024 | ||
| 520 | |a Aim Patients suffering from advanced colorectal cancer can experience unintended weight loss and/or treatment-induced gastrointestinal toxicity. Based on current evidence, the routine use of parenteral nutrition (PN) for patients with colorectal cancer is not recommended. This study evaluates the effect of PN supplementation on body composition, quality of life (QoL), chemotherapy-associated side effects and survival in patients with advanced colorectal cancer. Method Eighty-two patients with advanced colorectal cancer receiving a palliative chemotherapy were prospectively randomized to either oral enteral nutrition supplement (PN-) or oral enteral nutrition supplement plus supplemental PN (PN+). Every 6 weeks body weight, body mass index (BMI), chemotherapy-associated side effects and caloric intake were assessed, haemoglobin and serum albumin were measured. Body composition was assessed by body impedance analysis, and QoL was evaluated by European Organization for Research and Treatment of Cancer (EORTC) QLQC30 questionnaire. Results No differences were evident at baseline between the groups for age, sex, diagnosis, weight, BMI or QoL. A difference in BMI was observed by week 36, whereas differences of the mean body cell mass could be observed from week 6, albumin dropped significantly in the PN- group in week 36 and QoL showed significant differences from week 18. Chemotherapy-associated side effects were higher in PN-. The survival rate was significantly greater in the PN+ group. Conclusion A supplementation with PN slows weight loss, stabilizes body-composition and improves QoL in patients with advanced colorectal cancer. Furthermore, it can reduce chemotherapy-related side effects. | ||
| 650 | 4 | |a body composition | |
| 650 | 4 | |a chemotherapy | |
| 650 | 4 | |a colorectal cancer | |
| 650 | 4 | |a enteral nutrition | |
| 650 | 4 | |a palliative care | |
| 650 | 4 | |a Parenteral nutrition | |
| 700 | 1 | |a Essenbreis, Meike Kathrin |d 1979- |e VerfasserIn |0 (DE-588)1012065073 |0 (DE-627)704829428 |0 (DE-576)340388412 |4 aut | |
| 700 | 1 | |a Herold, Alexander |d 1956- |e VerfasserIn |0 (DE-588)131343637 |0 (DE-627)507960378 |0 (DE-576)298419025 |4 aut | |
| 700 | 1 | |a Post, Stefan |d 1954- |e VerfasserIn |0 (DE-588)1026227518 |0 (DE-627)726294667 |0 (DE-576)371524598 |4 aut | |
| 700 | 1 | |a Shang, Edward |d 1965- |e VerfasserIn |0 (DE-588)1076262120 |0 (DE-627)834585561 |0 (DE-576)175710171 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Colorectal disease |d Oxford [u.a.] : Wiley-Blackwell, 1999 |g 12(2010), 10, Seite e190-e199 |h Online-Ressource |w (DE-627)320440079 |w (DE-600)2004820-8 |w (DE-576)091142660 |x 1463-1318 |7 nnas |a Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment results from a prospective, randomized clinical trial |
| 773 | 1 | 8 | |g volume:12 |g year:2010 |g number:10 |g pages:e190-e199 |g extent:10 |a Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment results from a prospective, randomized clinical trial |
| 856 | 4 | 0 | |u https://doi.org/10.1111/j.1463-1318.2009.02111.x |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1463-1318.2009.02111.x |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20240312 | ||
| 993 | |a Article | ||
| 998 | |g 1012065073 |a Essenbreis, Meike Kathrin |m 1012065073:Essenbreis, Meike Kathrin |d 60000 |e 60000PE1012065073 |k 0/60000/ |p 2 | ||
| 998 | |g 1076262120 |a Shang, Edward |m 1076262120:Shang, Edward |d 60000 |d 61800 |e 60000PS1076262120 |e 61800PS1076262120 |k 0/60000/ |k 1/60000/61800/ |p 5 | ||
| 998 | |g 1026227518 |a Post, Stefan |m 1026227518:Post, Stefan |d 60000 |d 61800 |e 60000PP1026227518 |e 61800PP1026227518 |k 0/60000/ |k 1/60000/61800/ |p 4 | ||
| 998 | |g 124633315 |a Hasenberg, Till |m 124633315:Hasenberg, Till |d 60000 |d 61800 |e 60000PH124633315 |e 61800PH124633315 |k 0/60000/ |k 1/60000/61800/ |p 1 |x j | ||
| 999 | |a KXP-PPN1883186072 |e 4499561558 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"note":["Der Artikel wurde zurückgezogen","First published: 06 November 2009","Gesehen am 12.03.2024"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1883186072","language":["eng"],"person":[{"display":"Hasenberg, Till","roleDisplay":"VerfasserIn","role":"aut","family":"Hasenberg","given":"Till"},{"role":"aut","display":"Essenbreis, Meike Kathrin","roleDisplay":"VerfasserIn","given":"Meike Kathrin","family":"Essenbreis"},{"display":"Herold, Alexander","roleDisplay":"VerfasserIn","role":"aut","family":"Herold","given":"Alexander"},{"given":"Stefan","family":"Post","role":"aut","display":"Post, Stefan","roleDisplay":"VerfasserIn"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Shang, Edward","given":"Edward","family":"Shang"}],"title":[{"subtitle":"results from a prospective, randomized clinical trial","title":"Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment","title_sort":"Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment"}],"physDesc":[{"extent":"10 S."}],"relHost":[{"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisher":"Wiley-Blackwell ; Blackwell Science","dateIssuedKey":"1999","dateIssuedDisp":"1999-","publisherPlace":"Oxford [u.a.] ; Oxford"}],"id":{"zdb":["2004820-8"],"eki":["320440079"],"doi":["10.1111/(ISSN)1463-1318"],"issn":["1463-1318"]},"disp":"Early supplementation of parenteral nutrition is capable of improving quality of life, chemotherapy-related toxicity and body composition in patients with advanced colorectal carcinoma undergoing palliative treatment results from a prospective, randomized clinical trialColorectal disease","type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 27.10.03"],"recId":"320440079","language":["eng"],"pubHistory":["1.1999 -"],"part":{"extent":"10","volume":"12","text":"12(2010), 10, Seite e190-e199","issue":"10","pages":"e190-e199","year":"2010"},"title":[{"subtitle":"the official journal of the Association of Coloproctology of Great Britain and Ireland","title":"Colorectal disease","title_sort":"Colorectal disease"}]}],"name":{"displayForm":["T. Hasenberg, M. Essenbreis, A. Herold, S. Post, E. Shang"]},"origin":[{"dateIssuedDisp":"October 2010","dateIssuedKey":"2010"}],"id":{"doi":["10.1111/j.1463-1318.2009.02111.x"],"eki":["1883186072"]}} | ||
| SRT | |a HASENBERGTEARLYSUPPL2010 | ||