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Characterization of Austrian severe asthma patients

Introduction - The Severe Asthma Registry, founded by German Asthma Net (GAN) in 2011, is a prospective registry recording clinical parameters from participating centers in Germany, Austria and Switzerland. This article presents the baseline characteristics of severe asthma patients from Austrian ce...

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Main Authors: Renner, Andreas (Author) , Stoshikj, Slagjana (Author) , Pohl, Wolfgang (Author) , Bal, Christina (Author) , Reisinger, Matthias (Author) , Löffler-Ragg, Judith (Author) , Zacharasiewicz, Angela (Author) , Buhl, Roland (Author) , Hamelmann, Eckard (Author) , Taube, Christian (Author) , Korn, Stephanie (Author) , Idzko, Marco (Author)
Format: Article (Journal)
Language:English
Published: 10 October 2023
In: Respiratory medicine
Year: 2023, Volume: 219, Pages: 1-8
ISSN:1532-3064
DOI:10.1016/j.rmed.2023.107427
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.rmed.2023.107427
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0954611123003153
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Author Notes:Andreas Renner, Slagjana Stoshikj, Wolfgang Pohl, Christina Bal, Matthias Reisinger, Judith Löffler-Ragg, Angela Zacharasiewicz, Roland Buhl, Eckard Hamelmann, Christian Taube, Stephanie Korn, Marco Idzko
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Summary:Introduction - The Severe Asthma Registry, founded by German Asthma Net (GAN) in 2011, is a prospective registry recording clinical parameters from participating centers in Germany, Austria and Switzerland. This article presents the baseline characteristics of severe asthma patients from Austrian centers. - Methods - We analyzed the baseline visit data of all patients recruited to the GAN Severe Asthma Registry from participating Austrian centers. - Results - Baseline visit data were available for 214 Austrian severe asthma patients from 6 Austrian centers from 2013 to 2022. Mean age was 53.7 years. Mean BMI was 26.4 kg/m2. More than a third (37.4%) of all patients had daily daytime asthma symptoms at baseline and had to use their reliever medication at least once per day. Forty-one percent of patients were classified as uncontrolled according to GINA and 24.8% as partially controlled at baseline visit. The median annual exacerbation frequency was 3 in the previous 12 months. At the time of baseline visit, 23.4% of all patients had regular treatment with oral corticosteroids. Furthermore, 23.9% had received any severe asthma monoclonal antibody prior to the baseline visit. There were no notable differences in baseline characteristics between patients categorized by smoking history or measurable type 2 inflammation. - Conclusions - This study provides the first multi-center characterization of Austrian severe asthma patients. Patients in this cohort had better asthma control and less frequent exacerbations compared to most international registries.
Item Description:Gesehen am 18.03.2024
Physical Description:Online Resource
ISSN:1532-3064
DOI:10.1016/j.rmed.2023.107427

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