Economic evaluation of breast MRI in screening: a systematic review and basic approach to cost-effectiveness analyses

Background: Economic evaluations have become an accepted methodology for decision makers to allocate resources in healthcare systems. Particularly in screening, where short-term costs are associated with long-term benefits, and adverse effects of screening intermingle, cost-effectiveness analyses pr...

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Main Authors: Tollens, Fabian (Author) , Baltzer, Pascal A. T. (Author) , Froelich, Matthias F. (Author) , Kaiser, Clemens G. (Author)
Format: Article (Journal)
Language:English
Published: 07 December 2023
In: Frontiers in oncology
Year: 2023, Volume: 13, Pages: 1-14
ISSN:2234-943X
DOI:10.3389/fonc.2023.1292268
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3389/fonc.2023.1292268
Verlag, kostenfrei, Volltext: https://www.frontiersin.org/journals/oncology/articles/10.3389/fonc.2023.1292268/full
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Author Notes:Fabian Tollens, Pascal A.T. Baltzer, Matthias F. Froelich and Clemens G. Kaiser

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520 |a Background: Economic evaluations have become an accepted methodology for decision makers to allocate resources in healthcare systems. Particularly in screening, where short-term costs are associated with long-term benefits, and adverse effects of screening intermingle, cost-effectiveness analyses provide a means to estimate the economic value of screening. Purpose: To introduce the methodology of economic evaluations and to review the existing evidence on cost-effectiveness of MR-based breast cancer screening. Materials and methods: The various concepts and techniques of economic evaluations critical to the interpretation of cost-effectiveness analyses are briefly introduced. In a systematic review of the literature, economic evaluations from the years 2000-2022 are reviewed. Results: Despite a considerable heterogeneity in the reported input variables, outcome categories and methodological approaches, cost-effectiveness analyses report favorably on the economic value of breast MRI screening for different risk groups, including both short- and long-term costs and outcomes. Conclusion: Economic evaluations indicate a strongly favorable economic value of breast MRI screening for women at high risk and for women with dense breast tissue. 
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