Recurrence of congenital diaphragmatic hernia: risk factors, management, and future perspectives : perspective

Recurrence is one of the most common surgical complications in Congenital Diaphragmatic Hernia (CDH). It could remain clinically silent for a long time or present as an acute complication week, months, or even years after the primary surgery. Several risk factors have been identified so far. An exte...

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Hauptverfasser: Macchini, Francesco (VerfasserIn) , Raffaeli, Genny (VerfasserIn) , Amodeo, Ilaria (VerfasserIn) , Ichino, Martina (VerfasserIn) , Encinas, José Luis (VerfasserIn) , Martinez, Leopoldo (VerfasserIn) , Wessel, Lucas (VerfasserIn) , Cavallaro, Giacomo (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 09 February 2022
In: Frontiers in Pediatrics
Year: 2022, Jahrgang: 10, Pages: 1-6
ISSN:2296-2360
DOI:10.3389/fped.2022.823180
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.3389/fped.2022.823180
Verlag, kostenfrei, Volltext: https://www.frontiersin.org/articles/10.3389/fped.2022.823180
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Verfasserangaben:Francesco Macchini, Genny Raffaeli, Ilaria Amodeo, Martina Ichino, José Luis Encinas, Leopoldo Martinez, Lucas Wessel and Giacomo Cavallaro

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520 |a Recurrence is one of the most common surgical complications in Congenital Diaphragmatic Hernia (CDH). It could remain clinically silent for a long time or present as an acute complication week, months, or even years after the primary surgery. Several risk factors have been identified so far. An extended diaphragmatic defect represents one of the leading independent risk factors, together with indirect signs of large defect such as the liver position related to the diaphragm and the use of the prosthetic patch and with the use of a minimally invasive surgical (MIS) approach. However, the exact contribution of each factor and the overall risk of recurrence during the life span still need to be fully understood. This mini-review aims to give an overview of the current knowledge regarding CDH recurrence, focusing on predisposing factors, clinical presentation, management and follow-up of high-risk patients, and future perspectives. 
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