Unmasking pancreatic cancer: advanced biomedical imaging for its detection in native versus arterial dual-energy computed tomography (DECT) scans
This study investigates the potential of a machine learning classifier using dual- energy computed tomography (DECT) radiomics to differentiate between malignant pancreatic lesions and normal pancreas tissue. A total of 100 patients who underwent third-generation DECT between November 2018 and Octob...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , , , , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
14 February 2024
|
| In: |
International journal of imaging systems and technology
Year: 2024, Jahrgang: 34, Heft: 2, Pages: 1-9 |
| ISSN: | 1098-1098 |
| DOI: | 10.1002/ima.23037 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1002/ima.23037 Verlag, kostenfrei, Volltext: https://onlinelibrary.wiley.com/doi/abs/10.1002/ima.23037 
|
| Verfasserangaben: | Jennifer Gotta, Leon D. Gruenewald, Simon S. Martin, Christian Booz, Katrin Eichler, Scherwin Mahmoudi, Canan Özdemir Rezazadeh, Philipp Reschke, Teodora Biciusca, Lisa-Joy Juergens, Christoph Mader, Renate Hammerstingl, Christof M. Sommer, Thomas J. Vogl, Vitali Koch |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1889954144 | ||
| 003 | DE-627 | ||
| 005 | 20250612223847.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240527s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.1002/ima.23037 |2 doi | |
| 035 | |a (DE-627)1889954144 | ||
| 035 | |a (DE-599)KXP1889954144 | ||
| 035 | |a (OCoLC)1443679086 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Gotta, Jennifer |d 1997- |e VerfasserIn |0 (DE-588)1265512329 |0 (DE-627)1814396810 |4 aut | |
| 245 | 1 | 0 | |a Unmasking pancreatic cancer |b advanced biomedical imaging for its detection in native versus arterial dual-energy computed tomography (DECT) scans |c Jennifer Gotta, Leon D. Gruenewald, Simon S. Martin, Christian Booz, Katrin Eichler, Scherwin Mahmoudi, Canan Özdemir Rezazadeh, Philipp Reschke, Teodora Biciusca, Lisa-Joy Juergens, Christoph Mader, Renate Hammerstingl, Christof M. Sommer, Thomas J. Vogl, Vitali Koch |
| 264 | 1 | |c 14 February 2024 | |
| 300 | |a 9 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 27.05.2024 | ||
| 520 | |a This study investigates the potential of a machine learning classifier using dual- energy computed tomography (DECT) radiomics to differentiate between malignant pancreatic lesions and normal pancreas tissue. A total of 100 patients who underwent third-generation DECT between November 2018 and October 2022 were included, with 60 patients having pancreatic cancer and 40 normal pancreatic tissue. Radiomics features were extracted from non-contrast and arterial-enhanced DECT scans with stepwise feature reduction used to identify relevant features. Thetrained machine learning classifiers achieved a diagnostic accuracy of 0.97 in the arterial-enhanced model and 0.88 in non-contrast scans with sensitivities of 0.97 and 0.96, respectively. Areas under the curve were 0.97 (95% CI, 0.92-1.0, p < 0.001) and 0.96 (95% CI, 0.90-1.0, p < 0.001), respectively with no significant differences between both models (p= 0.52). This approach shows promise in enhancing pancreatic cancer detection and improving patient diagnoses, particulary in specific patient groups. | ||
| 650 | 4 | |a artificial intelligence | |
| 650 | 4 | |a dual-energy computed tomography | |
| 650 | 4 | |a machine learning | |
| 650 | 4 | |a pancreatic cancer | |
| 700 | 1 | |a Grünewald, Leon David |d 1991- |e VerfasserIn |0 (DE-588)1213268141 |0 (DE-627)1703781732 |4 aut | |
| 700 | 1 | |8 1\p |a Martin, Simon |d 1987- |e VerfasserIn |0 (DE-588)1072530090 |0 (DE-627)827692706 |0 (DE-576)434008044 |4 aut | |
| 700 | 1 | |8 2\p |a Booz, Christian |d 1989- |e VerfasserIn |0 (DE-588)1135674892 |0 (DE-627)89066269X |0 (DE-576)490027261 |4 aut | |
| 700 | 1 | |a Eichler, Katrin |d 1974- |e VerfasserIn |0 (DE-588)129617229 |0 (DE-627)475207114 |0 (DE-576)297750917 |4 aut | |
| 700 | 1 | |8 3\p |a Mahmoudi, Scherwin |d 1992- |e VerfasserIn |0 (DE-588)1215512481 |0 (DE-627)1726689840 |4 aut | |
| 700 | 1 | |8 4\p |a Özdemir-Rezazadeh, Canan |d 1987- |e VerfasserIn |0 (DE-588)1339551489 |0 (DE-627)1899182942 |4 aut | |
| 700 | 1 | |8 5\p |a Reschke, Philipp |d 1993- |e VerfasserIn |0 (DE-588)1228019215 |0 (DE-627)1749285495 |4 aut | |
| 700 | 1 | |8 6\p |a Biciusca, Teodora |e VerfasserIn |0 (DE-588)1273074270 |0 (DE-627)1822876257 |4 aut | |
| 700 | 1 | |a Juergens, Lisa-Joy |e VerfasserIn |4 aut | |
| 700 | 1 | |a Mader, Christoph |e VerfasserIn |0 (DE-588)1216726426 |0 (DE-627)1727991249 |4 aut | |
| 700 | 1 | |a Hammerstingl, Renate |d 1967- |e VerfasserIn |0 (DE-588)129629642 |0 (DE-627)475214722 |0 (DE-576)297757229 |4 aut | |
| 700 | 1 | |a Sommer, Christof-Matthias |d 1978- |e VerfasserIn |0 (DE-588)133929701 |0 (DE-627)558738699 |0 (DE-576)278278035 |4 aut | |
| 700 | 1 | |a Vogl, Thomas J. |d 1958- |e VerfasserIn |0 (DE-588)113728344 |0 (DE-627)503816558 |0 (DE-576)165097159 |4 aut | |
| 700 | 1 | |a Koch, Vitali |d 1985- |e VerfasserIn |0 (DE-588)1072017598 |0 (DE-627)826785611 |0 (DE-576)433486260 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t International journal of imaging systems and technology |d New York, NY [u.a.] : Wiley, 1989 |g 34(2024), 2, Artikel-ID 23037, Seite 1-9 |h Online-Ressource |w (DE-627)313587930 |w (DE-600)2009087-0 |w (DE-576)277977886 |x 1098-1098 |7 nnas |a Unmasking pancreatic cancer advanced biomedical imaging for its detection in native versus arterial dual-energy computed tomography (DECT) scans |
| 773 | 1 | 8 | |g volume:34 |g year:2024 |g number:2 |g elocationid:23037 |g pages:1-9 |g extent:9 |a Unmasking pancreatic cancer advanced biomedical imaging for its detection in native versus arterial dual-energy computed tomography (DECT) scans |
| 856 | 4 | 0 | |u https://doi.org/10.1002/ima.23037 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://onlinelibrary.wiley.com/doi/abs/10.1002/ima.23037 |x Verlag |z kostenfrei |3 Volltext |
| 883 | |8 1\p |a cgwrk |d 20250604 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 2\p |a cgwrk |d 20250604 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 3\p |a cgwrk |d 20250604 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 4\p |a cgwrk |d 20250604 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 5\p |a cgwrk |d 20250604 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 883 | |8 6\p |a cgwrk |d 20250604 |q DE-101 |u https://d-nb.info/provenance/plan#cgwrk | ||
| 951 | |a AR | ||
| 992 | |a 20240527 | ||
| 993 | |a Article | ||
| 994 | |a 2024 | ||
| 998 | |g 133929701 |a Sommer, Christof-Matthias |m 133929701:Sommer, Christof-Matthias |d 50000 |e 50000PS133929701 |k 0/50000/ |p 13 | ||
| 999 | |a KXP-PPN1889954144 |e 4530195163 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"person":[{"family":"Gotta","given":"Jennifer","roleDisplay":"VerfasserIn","display":"Gotta, Jennifer","role":"aut"},{"display":"Grünewald, Leon David","roleDisplay":"VerfasserIn","role":"aut","family":"Grünewald","given":"Leon David"},{"given":"Simon","family":"Martin","role":"aut","display":"Martin, Simon","roleDisplay":"VerfasserIn"},{"role":"aut","display":"Booz, Christian","roleDisplay":"VerfasserIn","given":"Christian","family":"Booz"},{"display":"Eichler, Katrin","roleDisplay":"VerfasserIn","role":"aut","family":"Eichler","given":"Katrin"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Mahmoudi, Scherwin","given":"Scherwin","family":"Mahmoudi"},{"family":"Özdemir-Rezazadeh","given":"Canan","display":"Özdemir-Rezazadeh, Canan","roleDisplay":"VerfasserIn","role":"aut"},{"display":"Reschke, Philipp","roleDisplay":"VerfasserIn","role":"aut","family":"Reschke","given":"Philipp"},{"family":"Biciusca","given":"Teodora","display":"Biciusca, Teodora","roleDisplay":"VerfasserIn","role":"aut"},{"given":"Lisa-Joy","family":"Juergens","role":"aut","display":"Juergens, Lisa-Joy","roleDisplay":"VerfasserIn"},{"family":"Mader","given":"Christoph","display":"Mader, Christoph","roleDisplay":"VerfasserIn","role":"aut"},{"given":"Renate","family":"Hammerstingl","role":"aut","roleDisplay":"VerfasserIn","display":"Hammerstingl, Renate"},{"role":"aut","display":"Sommer, Christof-Matthias","roleDisplay":"VerfasserIn","given":"Christof-Matthias","family":"Sommer"},{"given":"Thomas J.","family":"Vogl","role":"aut","display":"Vogl, Thomas J.","roleDisplay":"VerfasserIn"},{"roleDisplay":"VerfasserIn","display":"Koch, Vitali","role":"aut","family":"Koch","given":"Vitali"}],"title":[{"title_sort":"Unmasking pancreatic cancer","title":"Unmasking pancreatic cancer","subtitle":"advanced biomedical imaging for its detection in native versus arterial dual-energy computed tomography (DECT) scans"}],"note":["Gesehen am 27.05.2024"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1889954144","language":["eng"],"name":{"displayForm":["Jennifer Gotta, Leon D. Gruenewald, Simon S. Martin, Christian Booz, Katrin Eichler, Scherwin Mahmoudi, Canan Özdemir Rezazadeh, Philipp Reschke, Teodora Biciusca, Lisa-Joy Juergens, Christoph Mader, Renate Hammerstingl, Christof M. Sommer, Thomas J. Vogl, Vitali Koch"]},"origin":[{"dateIssuedKey":"2024","dateIssuedDisp":"14 February 2024"}],"id":{"doi":["10.1002/ima.23037"],"eki":["1889954144"]},"physDesc":[{"extent":"9 S."}],"relHost":[{"title":[{"title":"International journal of imaging systems and technology","title_sort":"International journal of imaging systems and technology"}],"titleAlt":[{"title":"Imaging systems and technology"}],"part":{"pages":"1-9","issue":"2","year":"2024","extent":"9","text":"34(2024), 2, Artikel-ID 23037, Seite 1-9","volume":"34"},"pubHistory":["1.1989 -"],"language":["eng"],"recId":"313587930","disp":"Unmasking pancreatic cancer advanced biomedical imaging for its detection in native versus arterial dual-energy computed tomography (DECT) scansInternational journal of imaging systems and technology","type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 27.08.10"],"id":{"issn":["1098-1098"],"eki":["313587930"],"doi":["10.1002/(ISSN)1098-1098"],"zdb":["2009087-0"]},"origin":[{"dateIssuedDisp":"1989-","publisher":"Wiley","dateIssuedKey":"1989","publisherPlace":"New York, NY [u.a.]"}],"physDesc":[{"extent":"Online-Ressource"}]}]} | ||
| SRT | |a GOTTAJENNIUNMASKINGP1420 | ||