Evaluation of an online-based self-help program for patients with generalized anxiety disorder: a randomized controlled trial

Objectives: This study aimed to evaluate the effects of an online self-help intervention for generalized anxiety disorder (GAD). Our primary outcomes were reductions in generalized anxiety symptoms, measured using the GAD-7 (Spitzer et al., 2006), and improvements in well-being based on the WHO-5 (T...

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Main Authors: Rubel, Julian (Author) , Väth, Teresa (Author) , Hanraths, Sofie (Author) , Prüßner, Luise (Author) , Timm, Christina (Author) , Hartmann, Steffen (Author) , Barnow, Sven (Author) , Lalk, Christopher (Author)
Format: Article (Journal) Chapter/Article
Language:English
Published: July 03, 2023
Edition:Draft version 1.1, Version 4
In: PsyArXiv preprints
Year: 2023, Pages: 1-45
DOI:10.31234/osf.io/kbhvy
Online Access:Resolving-System, kostenfrei, Volltext: https://doi.org/10.31234/osf.io/kbhvy
Verlag, kostenfrei, Volltext: https://osf.io/kbhvy
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Author Notes:Rubel, J., Väth, T., Hanraths, S., Pruessner, L., Timm, C., Hartmann, S., Barnow, S., Lalk, C.

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520 |a Objectives: This study aimed to evaluate the effects of an online self-help intervention for generalized anxiety disorder (GAD). Our primary outcomes were reductions in generalized anxiety symptoms, measured using the GAD-7 (Spitzer et al., 2006), and improvements in well-being based on the WHO-5 (Topp et al., 2015). - Methods: A total of 156 German-speaking patients aged 18 to 65 with a diagnosis of GAD and internet access were included in this randomized controlled trial. The intervention group (N = 78) received access to a 12-week online self-help program, while the waitlist control group (N = 78) received access only after the 12-week waiting period. - Results: The intervention group showed a significant improvement in generalized anxiety symptoms compared to the control group (t(df=123.73) = -4.52, p < .001) with a medium to large effect size (d = -0.88, 95%-CI: -1.26; -0.50). Additionally, the intervention group demonstrated a significant increase in quality of life compared to the control group (t(df=87,86) = 3.48, p < .001), with a moderate to large effect size (d = 0.62, 95% CI: 0.27; 0.98). However, no significant effects were observed for secondary outcomes of functional impairments, work productivity, mental health literacy, and healthcare demands. For exploratory outcomes, improvement was found for anxiety and worry symptoms. - Conclusions: These findings suggest that an online-based self-help intervention effectively reduces core GAD symptoms and improves overall quality of life. Future research should explore the long-term effects of this intervention and investigate potential mechanisms underlying its effectiveness. 
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