Synthesis of 6-epi- and 4,6-bisepi-N-acetyl-D-neuraminic acid by aldol condensation
Reaction of allofurano-2, 3-oxazoline 2 with potassium ditert. butyl oxaloacetate afforded the two diastereomeric compounds 3 and 3a which, after deblocking and alkaline treatment, are converted to the two epimeric sialic acids 5 and 5a.
Gespeichert in:
| Hauptverfasser: | , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
31 March 1992
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| In: |
Tetrahedron letters
Year: 1992, Jahrgang: 33, Heft: 14, Pages: 1867-1870 |
| ISSN: | 1873-3581 |
| DOI: | 10.1016/S0040-4039(00)74163-3 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/S0040-4039(00)74163-3 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S0040403900741633 
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| Verfasserangaben: | Hans Mack and Reinhard Brossmer |
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| 520 | |a Reaction of allofurano-2, 3-oxazoline 2 with potassium ditert. butyl oxaloacetate afforded the two diastereomeric compounds 3 and 3a which, after deblocking and alkaline treatment, are converted to the two epimeric sialic acids 5 and 5a. | ||
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