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Low rate of function-limiting side effects with high-dose adjuvant radiotherapy in high-grade soft tissue extremity sarcomas: a retrospective single-center analysis over 10 years

Over the years, radiotherapy has been established as a tool to improve local control for high-grade sarcomas. Although the European Society for Medical Oncology guidelines has taken notice of a shift toward a neoadjuvant radiotherapy approach, the American Society for Radiation Oncology guidelines c...

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Hauptverfasser: Köksal, Mümtaz (VerfasserIn) , van der Hoek, Maike (VerfasserIn) , Scafa, Davide (VerfasserIn) , Koch, David (VerfasserIn) , Leitzen, Christina (VerfasserIn) , Schmeel, Leonard C. (VerfasserIn) , Feldmann, Georg (VerfasserIn) , Strauss, Andreas (VerfasserIn) , Koob, Sebastian (VerfasserIn) , Giordano, Frank Anton (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: July 2023
In: Journal of cancer research and clinical oncology
Year: 2023, Jahrgang: 149, Heft: 8, Pages: 4877-4888
ISSN:1432-1335
DOI:10.1007/s00432-022-04423-1
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00432-022-04423-1
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00432-022-04423-1
Volltext
Verfasserangaben:Muemtaz Koeksal, Maike van der Hoek, Davide Scafa, David Koch, Christina Leitzen, Leonard C. Schmeel, Georg Feldmann, Andreas Strauss, Sebastian Koob, Frank A. Giordano
Beschreibung
Zusammenfassung:Over the years, radiotherapy has been established as a tool to improve local control for high-grade sarcomas. Although the European Society for Medical Oncology guidelines has taken notice of a shift toward a neoadjuvant radiotherapy approach, the American Society for Radiation Oncology guidelines clearly favor a neoadjuvant approach, citing debilitating long-term adverse effects when radiotherapy is applied postoperatively. In this study, we examined these irradiation-associated adverse events for adjuvant radiotherapy and focused on the prognostic factors for disease outcome, including local control.
Beschreibung:Online veröffentlicht: 26. Oktober 2022
Gesehen am 01.07.2024
Beschreibung:Online Resource
ISSN:1432-1335
DOI:10.1007/s00432-022-04423-1

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