Systemic inflammatory biomarkers as predictive and prognostic factors in men with metastatic castration-refractory prostate cancer treated with docetaxel therapy: a comprehensive analysis in a German real-world cohort
Advances in therapy of metastatic castration-refractory prostate cancer (mCRPC) resulted in more therapeutic options and led to a higher need of predictive/prognostic biomarkers. Systemic inflammatory biomarkers could provide the basis for personalized treatment selection. This study aimed to assess...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
July 2023
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| In: |
Journal of cancer research and clinical oncology
Year: 2023, Volume: 149, Issue: 7, Pages: 3371-3381 |
| ISSN: | 1432-1335 |
| DOI: | 10.1007/s00432-022-04220-w |
| Online Access: | Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00432-022-04220-w Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00432-022-04220-w 
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| Author Notes: | Manuel Neuberger, Nora Goly, Janina Skladny, Veronica Milczynski, Christel Weiß, Frederik Wessels, Katja Nitschke, Britta Grüne, Caelán M. Haney, Friedrich Hartung, Jonas Herrmann, Jonas Jarczyk, Karl F. Kowalewski, Frank Waldbillig, Maximilian C. Kriegmair, Niklas Westhoff, Thomas S. Worst, Philipp Nuhn |
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| 520 | |a Advances in therapy of metastatic castration-refractory prostate cancer (mCRPC) resulted in more therapeutic options and led to a higher need of predictive/prognostic biomarkers. Systemic inflammatory biomarkers could provide the basis for personalized treatment selection. This study aimed to assess the modified Glasgow Prognostic Score (mGPS), the neutrophile-to-lymphocyte ratio (NLR), the platelet-to-lymphocyte ratio (PLR) and the systemic immune-inflammation index (SII) in men with mCRPC under docetaxel. | ||
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