Computed diffusion-weighted imaging in patients with transient neurovascular symptoms with and without ischemic infarction
PURPOSE: Detection of ischemic lesions in patients with transient neurovascular symptoms is relevant for the estimation of the risk of a subsequent stroke and etiological classification. To improve detection rates, different technical approaches have been used, such as diffusion-weighted imaging (DW...
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| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
2024
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| In: |
Journal of neuroradiology
Year: 2024, Jahrgang: 51, Heft: 1, Pages: 1-4 |
| ISSN: | 1773-0406 |
| DOI: | 10.1007/10.1016/j.neurad.2023.02.007 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/10.1016/j.neurad.2023.02.007
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| Verfasserangaben: | A. Förster, Ana Ramos, H. Wenz, C. Groden, A. Alonso |
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| 245 | 1 | 0 | |a Computed diffusion-weighted imaging in patients with transient neurovascular symptoms with and without ischemic infarction |c A. Förster, Ana Ramos, H. Wenz, C. Groden, A. Alonso |
| 264 | 1 | |c 2024 | |
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| 520 | |a PURPOSE: Detection of ischemic lesions in patients with transient neurovascular symptoms is relevant for the estimation of the risk of a subsequent stroke and etiological classification. To improve detection rates, different technical approaches have been used, such as diffusion-weighted imaging (DWI) with high b-values or higher magnetic field strength. Here, we sought to investigate the value of computed DWI (cDWI) with high b-values in these patients. - METHODS: From an MRI report database we identified patients with transient neurovascular symptoms who underwent repeated MRI including DWI. cDWI was calculated with a monoexponential model with high b-values (2000, 3000, and 4000 s/mm2) and compared to the routinely used standard DWI with regard to presence of ischemic lesions and lesion detectability. - RESULT: Overall 33 patients with transient neurovascular symptoms (71 [IQR 57-83.5] years; 21 [63.6%] male) were included. On DWI, acute ischemic lesions were observed in 22 (78.6%). Acute ischemic lesions were observed in 17 (51.5%) patients on initial DWI, and in 26 (78.8%) patients on follow-up DWI. Lesion detectability was rated significantly better on cDWI at 2000s/mm2 compared to standard DWI. In 2 (9.1%) patients, cDWI at 2000s/mm2 revealed an acute ischemic lesion proven on follow-up standard DWI which was not detected with certainty on the initial standard DWI. - CONCLUSION: cDWI might be a valuable addition to routinely acquired standard DWI in patients with transient neurovascular symptoms since its use might result in improved ischemic lesion detection. A b-value of 2000s/mm2 seems most promising for clinical practice. | ||
| 650 | 4 | |a cDWI | |
| 650 | 4 | |a computed DWI | |
| 650 | 4 | |a Diffusion Magnetic Resonance Imaging | |
| 650 | 4 | |a Female | |
| 650 | 4 | |a Humans | |
| 650 | 4 | |a Infarction | |
| 650 | 4 | |a Ischemic Attack, Transient | |
| 650 | 4 | |a Ischemic lesion | |
| 650 | 4 | |a Male | |
| 650 | 4 | |a Stroke | |
| 650 | 4 | |a Transient ischemic attack | |
| 650 | 4 | |a Transient neurovascular symptoms | |
| 700 | 1 | |a Ramos, Ana |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wenz, Holger |d 1983- |e VerfasserIn |0 (DE-588)103347178X |0 (DE-627)741282755 |0 (DE-576)381071057 |4 aut | |
| 700 | 1 | |a Groden, Christoph |d 1959- |e VerfasserIn |0 (DE-588)11292641X |0 (DE-627)691165742 |0 (DE-576)331358948 |4 aut | |
| 700 | 1 | |a Alonso, Angelika |d 1977- |e VerfasserIn |0 (DE-588)1025166795 |0 (DE-627)721355315 |0 (DE-576)370025865 |4 aut | |
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