Intraoperative or postoperative stereotactic radiotherapy for brain metastases: time to systemic treatment onset and other patient-relevant outcomes

Intraoperative radiotherapy (IORT) has become a viable treatment option for resectable brain metastases (BMs). As data on local control and radiation necrosis rates are maturing, we focus on meaningful secondary endpoints such as time to next treatment (TTNT), duration of postoperative corticosteroi...

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Main Authors: Dejonckheere, Cas S. (Author) , Layer, Julian P. (Author) , Hamed, Motaz (Author) , Layer, Katharina (Author) , Glasmacher, Andrea (Author) , Friker, Lea L. (Author) , Potthoff, Anna-Laura (Author) , Zeyen, Thomas (Author) , Scafa, Davide (Author) , Koch, David (Author) , Garbe, Stephan (Author) , Holz, Jasmin A. (Author) , Kugel, Fabian (Author) , Grimmer, Molina (Author) , Schmeel, Frederic Carsten (Author) , Gielen, Gerrit H. (Author) , Forstbauer, Helmut (Author) , Vatter, Hartmut (Author) , Herrlinger, Ulrich (Author) , Giordano, Frank Anton (Author) , Schneider, Matthias (Author) , Schmeel, Leonard Christopher (Author) , Sarria, Gustavo R. (Author)
Format: Article (Journal)
Language:English
Published: September 2023
In: Journal of neuro-oncology
Year: 2023, Volume: 164, Issue: 3, Pages: 683-691
ISSN:1573-7373
DOI:10.1007/s11060-023-04464-7
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s11060-023-04464-7
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s11060-023-04464-7
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Author Notes:Cas S. Dejonckheere, Julian P. Layer, Motaz Hamed, Katharina Layer, Andrea Glasmacher, Lea L. Friker, Anna-Laura Potthoff, Thomas Zeyen, Davide Scafa, David Koch, Stephan Garbe, Jasmin A. Holz, Fabian Kugel, Molina Grimmer, Frederic Carsten Schmeel, Gerrit H. Gielen, Helmut Forstbauer, Hartmut Vatter, Ulrich Herrlinger, Frank A. Giordano, Matthias Schneider, Leonard Christopher Schmeel, Gustavo R. Sarria
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Summary:Intraoperative radiotherapy (IORT) has become a viable treatment option for resectable brain metastases (BMs). As data on local control and radiation necrosis rates are maturing, we focus on meaningful secondary endpoints such as time to next treatment (TTNT), duration of postoperative corticosteroid treatment, and in-hospital time.
Item Description:Online veröffentlicht: 9. Oktober 2023
Gesehen am 15.07.2024
Physical Description:Online Resource
ISSN:1573-7373
DOI:10.1007/s11060-023-04464-7