G Protein Coupled Receptor 87 (GPR87) in end stage kidney and associated tumors
Background/Aim: End-stage renal disease (ESRD) and acquired cystic renal disease (ACRD) are characterized by progressive inflammation, structural remodeling and by development of unique cancer types. Eosinophilic-vacuolated and chromophobe-like renal cell carcinoma develop exclusively in ACRD kidney...
Gespeichert in:
| Hauptverfasser: | , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
February 2024
|
| In: |
Anticancer research
Year: 2024, Jahrgang: 44, Heft: 2, Pages: 555-559 |
| ISSN: | 1791-7530 |
| DOI: | 10.21873/anticanres.16843 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.21873/anticanres.16843 Verlag, lizenzpflichtig, Volltext: https://ar.iiarjournals.org/content/44/2/555-0 
|
| Verfasserangaben: | Tamas Beothe, Gyula Kovacs, Lehel Peterfi |
MARC
| LEADER | 00000caa a22000002c 4500 | ||
|---|---|---|---|
| 001 | 1895990475 | ||
| 003 | DE-627 | ||
| 005 | 20241205153506.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 240722s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.21873/anticanres.16843 |2 doi | |
| 035 | |a (DE-627)1895990475 | ||
| 035 | |a (DE-599)KXP1895990475 | ||
| 035 | |a (OCoLC)1475303589 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Beöthe, Tamás |d 1973- |e VerfasserIn |0 (DE-588)1156311438 |0 (DE-627)1018864024 |0 (DE-576)502100796 |4 aut | |
| 245 | 1 | 0 | |a G Protein Coupled Receptor 87 (GPR87) in end stage kidney and associated tumors |c Tamas Beothe, Gyula Kovacs, Lehel Peterfi |
| 246 | 3 | 0 | |a eightyseven |
| 264 | 1 | |c February 2024 | |
| 300 | |a 5 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Online veröffentlicht: 2. Februar 2024 | ||
| 500 | |a Gesehen am 22.07.2024 | ||
| 520 | |a Background/Aim: End-stage renal disease (ESRD) and acquired cystic renal disease (ACRD) are characterized by progressive inflammation, structural remodeling and by development of unique cancer types. Eosinophilic-vacuolated and chromophobe-like renal cell carcinoma develop exclusively in ACRD kidney. The aim of the study was to investigate the molecular mechanism of ESRD/ACRD carcinogenesis. Materials and Methods: Our previous Affymetrix array analysis detected GPR87 as one of the highly and specifically expressed genes in ESRD/ACRD kidneys. In this study we analyzed normal and ESRD/ACRD kidneys and related tumors for GPR87 expression by PCR, RT-PCR, and immunohistochemistry. Results: Immunohistochemistry revealed a strong GPR87 expression in proliferating epithelial cells in ESRD/ACRD kidneys and in cells of eosinophilic-vacuolated and chromophobe-like renal cell carcinoma. Conclusion: GPR87 signaling plays an important role in the structural remodeling of ESRD/ACRD kidney and development of ACRD-associated tumors with unique histology. | ||
| 650 | 4 | |a carcinogenesis | |
| 650 | 4 | |a end stage kidney | |
| 650 | 4 | |a GPR87 | |
| 700 | 1 | |a Kovacs, Gyula |e VerfasserIn |0 (DE-588)1081747579 |0 (DE-627)846587424 |0 (DE-576)454756399 |4 aut | |
| 700 | 1 | |a Peterfi, Lehel |e VerfasserIn |0 (DE-588)1187980692 |0 (DE-627)1666944742 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Anticancer research |d Kapandriti, Attiki, Greece : International Institute of Anticancer Research, 2004 |g 44(2024), 2, Seite 555-559 |h Online-Ressource |w (DE-627)387478493 |w (DE-600)2145376-7 |w (DE-576)358408717 |x 1791-7530 |7 nnas |a G Protein Coupled Receptor 87 (GPR87) in end stage kidney and associated tumors |
| 773 | 1 | 8 | |g volume:44 |g year:2024 |g number:2 |g pages:555-559 |g extent:5 |a G Protein Coupled Receptor 87 (GPR87) in end stage kidney and associated tumors |
| 856 | 4 | 0 | |u https://doi.org/10.21873/anticanres.16843 |x Verlag |x Resolving-System |z lizenzpflichtig |3 Volltext |
| 856 | 4 | 0 | |u https://ar.iiarjournals.org/content/44/2/555-0 |x Verlag |z lizenzpflichtig |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20240722 | ||
| 993 | |a Article | ||
| 994 | |a 2024 | ||
| 998 | |g 1081747579 |a Kovacs, Gyula |m 1081747579:Kovacs, Gyula |d 50000 |e 50000PK1081747579 |k 0/50000/ |p 2 | ||
| 999 | |a KXP-PPN1895990475 |e 4555377192 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"language":["eng"],"recId":"1895990475","type":{"media":"Online-Ressource","bibl":"article-journal"},"note":["Online veröffentlicht: 2. Februar 2024","Gesehen am 22.07.2024"],"title":[{"title":"G Protein Coupled Receptor 87 (GPR87) in end stage kidney and associated tumors","title_sort":"G Protein Coupled Receptor 87 (GPR87) in end stage kidney and associated tumors"}],"person":[{"family":"Beöthe","given":"Tamás","roleDisplay":"VerfasserIn","display":"Beöthe, Tamás","role":"aut"},{"family":"Kovacs","given":"Gyula","roleDisplay":"VerfasserIn","display":"Kovacs, Gyula","role":"aut"},{"family":"Peterfi","given":"Lehel","display":"Peterfi, Lehel","roleDisplay":"VerfasserIn","role":"aut"}],"relHost":[{"pubHistory":["Nachgewiesen 24.2004 -"],"part":{"issue":"2","pages":"555-559","year":"2024","extent":"5","volume":"44","text":"44(2024), 2, Seite 555-559"},"note":["Gesehen am 26.02.13"],"type":{"bibl":"periodical","media":"Online-Ressource"},"disp":"G Protein Coupled Receptor 87 (GPR87) in end stage kidney and associated tumorsAnticancer research","recId":"387478493","language":["eng"],"title":[{"title":"Anticancer research","subtitle":"international journal of cancer research and treatment","title_sort":"Anticancer research"}],"physDesc":[{"extent":"Online-Ressource"}],"origin":[{"publisherPlace":"Kapandriti, Attiki, Greece","dateIssuedDisp":"2004-","dateIssuedKey":"2004","publisher":"International Institute of Anticancer Research"}],"id":{"issn":["1791-7530"],"eki":["387478493"],"zdb":["2145376-7"]},"name":{"displayForm":["International Institute of Anticancer Research"]}}],"physDesc":[{"extent":"5 S."}],"id":{"eki":["1895990475"],"doi":["10.21873/anticanres.16843"]},"origin":[{"dateIssuedKey":"2024","dateIssuedDisp":"February 2024"}],"name":{"displayForm":["Tamas Beothe, Gyula Kovacs, Lehel Peterfi"]}} | ||
| SRT | |a BEOETHETAMGPROTEINCO2024 | ||