Function-guided differences of arcuate fascicle and inferior fronto-occipital fascicle tractography as diagnostic indicators for surgical risk stratification

Several patients with language-eloquent gliomas face language deterioration postoperatively. Persistent aphasia is frequently associated with damage to subcortical language pathways. Underlying mechanisms still need to be better understood, complicating preoperative risk assessment. This study compa...

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Hauptverfasser: Kram, Leonie (VerfasserIn) , Schroeder, Axel (VerfasserIn) , Meyer, Bernhard (VerfasserIn) , Krieg, Sandro (VerfasserIn) , Ille, Sebastian (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 10 April 2024
In: Brain structure & function
Year: 2024, Jahrgang: 229, Pages: 2219–2235
ISSN:1863-2661
DOI:10.1007/s00429-024-02787-3
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00429-024-02787-3
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Verfasserangaben:Leonie Kram, Axel Schroeder, Bernhard Meyer, Sandro M. Krieg, Sebastian Ille

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520 |a Several patients with language-eloquent gliomas face language deterioration postoperatively. Persistent aphasia is frequently associated with damage to subcortical language pathways. Underlying mechanisms still need to be better understood, complicating preoperative risk assessment. This study compared qualitative and quantitative functionally relevant subcortical differences pre- and directly postoperatively in glioma patients with and without aphasia. 
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