Cover Image

Decreased alloreactivity after vaccination against hepatitis B

The beneficial effect of blood transfusions on renal allografts disappeared at about the same time when hepatitis B vaccination was introduced in dialysis patients. To determine possible immunosuppressive effects of hepatitis B vaccination, we studied alloreactivity during the course of immunization...

Full description

Saved in:
Bibliographic Details
Main Authors: Ruder, Hans (Author) , Kerling, Frank (Author) , Daniel, Volker (Author) , Korn, Klaus (Author) , Waßmuth, Ralf (Author)
Format: Article (Journal)
Language:English
Published: May 15, 1995
In: Transplantation
Year: 1995, Volume: 59, Issue: 9, Pages: 1339-1342
ISSN:1534-6080
Online Access:Verlag, lizenzpflichtig, Volltext: https://journals.lww.com/transplantjournal/abstract/1995/05150/decreased_alloreactivity_after_vaccination_against.20.aspx
Get full text
Author Notes:Hans Ruder, Frank Kerling, Volker Daniel, Klaus Korn, Ralf Wassmuth

MARC

LEADER 00000caa a2200000 c 4500
001 1899366245
003 DE-627
005 20241205164606.0
007 cr uuu---uuuuu
008 240822s1995 xx |||||o 00| ||eng c
035 |a (DE-627)1899366245 
035 |a (DE-599)KXP1899366245 
035 |a (OCoLC)1475308954 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Ruder, Hans  |e VerfasserIn  |0 (DE-588)1339825295  |0 (DE-627)189936580X  |4 aut 
245 1 0 |a Decreased alloreactivity after vaccination against hepatitis B  |c Hans Ruder, Frank Kerling, Volker Daniel, Klaus Korn, Ralf Wassmuth 
264 1 |c May 15, 1995 
300 |a 4 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 22.08.2024 
520 |a The beneficial effect of blood transfusions on renal allografts disappeared at about the same time when hepatitis B vaccination was introduced in dialysis patients. To determine possible immunosuppressive effects of hepatitis B vaccination, we studied alloreactivity during the course of immunization. Fourteen healthy subjects without serological evidence of hepatitis B were routinely immunized against hepatitis B surface antigen. Plasma and mononuclear cells were isolated and frozen before immunization and after vaccination, respectively. Mean alloreactivity measured by [3H]thymidine uptake decreased from 64,772 cpm before immunization to 40,213 cpm after the third immunization. In crossover experiments, cellular modulation and plasma-dependent modulation of alloreactivity were observed. The immunosuppressive effect of plasma taken 4 weeks after the third vaccination correlated (r=0.9) highly significantly (P<0.005) with the anti-hepatitis B surface antigen antibody titer. Taken together, our data strongly suggest that hepatitis B vaccination is capable of reducing allogenic reactivity. 
700 1 |a Kerling, Frank  |e VerfasserIn  |4 aut 
700 1 |a Daniel, Volker  |e VerfasserIn  |0 (DE-588)1058939513  |0 (DE-627)79784418X  |0 (DE-576)166309168  |4 aut 
700 1 |a Korn, Klaus  |d 1938-  |e VerfasserIn  |0 (DE-588)1222681528  |0 (DE-627)1741844002  |4 aut 
700 1 |a Waßmuth, Ralf  |d 1960-  |e VerfasserIn  |0 (DE-588)111579376  |0 (DE-627)501837663  |0 (DE-576)289706556  |4 aut 
773 0 8 |i Enthalten in  |t Transplantation  |d Hagerstown, Md. : Lippincott Williams & Wilkins, 1963  |g 59(1995), 9, Seite 1339-1342  |h Online-Ressource  |w (DE-627)32529738X  |w (DE-600)2035395-9  |w (DE-576)097188794  |x 1534-6080  |7 nnas  |a Decreased alloreactivity after vaccination against hepatitis B 
773 1 8 |g volume:59  |g year:1995  |g number:9  |g pages:1339-1342  |g extent:4  |a Decreased alloreactivity after vaccination against hepatitis B 
856 4 0 |u https://journals.lww.com/transplantjournal/abstract/1995/05150/decreased_alloreactivity_after_vaccination_against.20.aspx  |x Verlag  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20240822 
993 |a Article 
994 |a 1995 
998 |g 1058939513  |a Daniel, Volker  |m 1058939513:Daniel, Volker  |d 910000  |d 911600  |e 910000PD1058939513  |e 911600PD1058939513  |k 0/910000/  |k 1/910000/911600/  |p 3 
999 |a KXP-PPN1899366245  |e 4569747493 
BIB |a Y 
SER |a journal 
JSO |a {"person":[{"role":"aut","display":"Ruder, Hans","roleDisplay":"VerfasserIn","given":"Hans","family":"Ruder"},{"given":"Frank","family":"Kerling","role":"aut","roleDisplay":"VerfasserIn","display":"Kerling, Frank"},{"role":"aut","roleDisplay":"VerfasserIn","display":"Daniel, Volker","given":"Volker","family":"Daniel"},{"given":"Klaus","family":"Korn","role":"aut","roleDisplay":"VerfasserIn","display":"Korn, Klaus"},{"given":"Ralf","family":"Waßmuth","role":"aut","roleDisplay":"VerfasserIn","display":"Waßmuth, Ralf"}],"title":[{"title_sort":"Decreased alloreactivity after vaccination against hepatitis B","title":"Decreased alloreactivity after vaccination against hepatitis B"}],"note":["Gesehen am 22.08.2024"],"type":{"bibl":"article-journal","media":"Online-Ressource"},"recId":"1899366245","language":["eng"],"name":{"displayForm":["Hans Ruder, Frank Kerling, Volker Daniel, Klaus Korn, Ralf Wassmuth"]},"origin":[{"dateIssuedKey":"1995","dateIssuedDisp":"May 15, 1995"}],"id":{"eki":["1899366245"]},"physDesc":[{"extent":"4 S."}],"relHost":[{"id":{"eki":["32529738X"],"zdb":["2035395-9"],"issn":["1534-6080"]},"origin":[{"publisherPlace":"Hagerstown, Md. ; [Erscheinungsort nicht ermittelbar]","dateIssuedDisp":"1963-","dateIssuedKey":"1963","publisher":"Lippincott Williams & Wilkins ; Ovid"}],"physDesc":[{"extent":"Online-Ressource"}],"title":[{"title_sort":"Transplantation","subtitle":"the official journal of the Transplantation Society","title":"Transplantation"}],"corporate":[{"role":"isb","display":"Transplantation Society","roleDisplay":"Herausgebendes Organ"}],"language":["eng"],"recId":"32529738X","type":{"media":"Online-Ressource","bibl":"periodical"},"note":["Gesehen am 11.06.2019"],"disp":"Decreased alloreactivity after vaccination against hepatitis BTransplantation","part":{"year":"1995","pages":"1339-1342","issue":"9","volume":"59","text":"59(1995), 9, Seite 1339-1342","extent":"4"},"pubHistory":["1.1963 -"]}]} 
SRT |a RUDERHANSKDECREASEDA1519 

Similar Items