Identification of the UL56 protein of herpes simplex virus type 1 within the virion by immuno electron microscopy

Recently the UL56 protein of herpes simplex virus type 1 (HSV-1) was shown to be associated with the virion of HSV-1 as determined by Western blot analysis. The detection of the UL56 protein in infected cells and its association with virions of HSV-1 is of particular importance, pointing to a possib...

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Hauptverfasser: Kehm, Roland (VerfasserIn) , Gelderblom, Hans R. (VerfasserIn) , Darai, Gholamreza (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: July 1998
In: Virus genes
Year: 1998, Jahrgang: 17, Heft: 1, Pages: 49-53
ISSN:1572-994X
DOI:10.1023/A:1008053017716
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1023/A:1008053017716
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Verfasserangaben:Roland Kehm, Hans R. Gelderblom, Gholamreza Darai
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Zusammenfassung:Recently the UL56 protein of herpes simplex virus type 1 (HSV-1) was shown to be associated with the virion of HSV-1 as determined by Western blot analysis. The detection of the UL56 protein in infected cells and its association with virions of HSV-1 is of particular importance, pointing to a possible involvement of UL56 protein in virus-host interactions. In order to investigate the properties of the UL56 protein further immuno-localization was performed using rabbit hyperimmune serum against fusion recombinant UL56 protein and purified virions of HSV-1 strain F. The UL56 protein was detected in the HSV-1 virions by immuno gold negative staining.
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Beschreibung:Online Resource
ISSN:1572-994X
DOI:10.1023/A:1008053017716