Comparative efficacy of talquetamab vs. current treatments in the LocoMMotion and MoMMent studies in patients with triple-class-exposed relapsed/refractory multiple myeloma
Talquetamab, a bispecific antibody targeting GPRC5D × CD3, is approved for the treatment of patients with triple-class -exposed (TCE) relapsed/refractory multiple myeloma (RRMM) on the basis of the results from the phase I/II MonumenTAL-1 trial. The relative effectiveness of talquetamab vs. real-wor...
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| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article (Journal) |
| Language: | English |
| Published: |
24 February 2024
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| In: |
Advances in therapy
Year: 2024, Volume: 41, Issue: 4, Pages: 1576-1593 |
| ISSN: | 1865-8652 |
| DOI: | 10.1007/s12325-024-02797-x |
| Online Access: | Resolving-System, kostenfrei, Volltext: https://doi.org/10.1007/s12325-024-02797-x Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s12325-024-02797-x |
| Author Notes: | Hermann Einsele, Philippe Moreau, Nizar Bahlis, Manisha Bhutani, Laure Vincent, Lionel Karlin, Aurore Perrot, Hartmut Goldschmidt, Niels W. C. J. van de Donk, Enrique M. Ocio, Joaquin Martinez-Lopez, Paula Rodríguez-Otero, Dominik Dytfeld, Joris Diels, Vadim Strulev, Imene Haddad, Thomas Renaud, Eric Ammann, Jedelyn Cabrieto, Nolen Perualila, Ryan Gan, Youyi Zhang, Trilok Parekh, Claire Albrecht, Katja Weisel, Maria-Victoria Mateos |
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| 520 | |a Talquetamab, a bispecific antibody targeting GPRC5D × CD3, is approved for the treatment of patients with triple-class -exposed (TCE) relapsed/refractory multiple myeloma (RRMM) on the basis of the results from the phase I/II MonumenTAL-1 trial. The relative effectiveness of talquetamab vs. real-world physician’s choice of therapy (RWPC) was assessed using adjusted comparisons. | ||
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