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Beyond biopsychosocial: the keystone mechanism theory of pain

Pain is a deeply personal experience, with interindividual differences in its chronification and treatment presenting a formidable healthcare challenge. The biopsychosocial model (BPSm) has been hugely influential within nascent attempts at precision pain medicine, steering the field away from a red...

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Hauptverfasser: Lawn, Timothy (VerfasserIn) , Sendel, Manon (VerfasserIn) , Baron, Ralf (VerfasserIn) , Vollert, Jan (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: November 2023
In: Brain, behavior and immunity
Year: 2023, Jahrgang: 114, Pages: 187-192
ISSN:1090-2139
DOI:10.1016/j.bbi.2023.08.018
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.bbi.2023.08.018
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S0889159123002416
Volltext
Verfasserangaben:Timothy Lawn, Manon Sendel, Ralf Baron, Jan Vollert

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520 |a Pain is a deeply personal experience, with interindividual differences in its chronification and treatment presenting a formidable healthcare challenge. The biopsychosocial model (BPSm) has been hugely influential within nascent attempts at precision pain medicine, steering the field away from a reductionist biomechanical viewpoint and emphasising complex interactions of biological, psychological, and social factors which shape the individuality of pain. However, despite offering a strong theoretical foundation and holistic perspective, we contend that the BPSm remains limited in its capacity to deliver truly mechanistically informed treatment of pain. We therefore propose the keystone model of pain which offers a pragmatic balance between the dimensionality expansive BPSm and overly reductive approaches, providing both theoretical and practical advantages for the transition from treating populations to individual people. 
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