Identifying metabolic features of colorectal cancer liability using Mendelian randomization

Increased genetic liability to colorectal cancer is associated with altered levels of circulating metabolites, including fatty acids, up to 40 years before average age of diagnosis.

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Bibliographic Details
Main Authors:	Bull, Caroline J. (Author) , Hazelwood, Emma (Author) , Bell, Joshua Alexander (Author) , Tan, Vanessa (Author) , Constantinescu, Andrei-Emil (Author) , Borges, Carolina (Author) , Legge, Danny (Author) , Burrows, Kimberley (Author) , Huyghe, Jeroen R. (Author) , Brenner, Hermann (Author) , Castellvi-Bel, Sergi (Author) , Chan, Andrew T. (Author) , Kweon, Sun-Seog (Author) , Marchand, Loic Le (Author) , Li, Li (Author) , Cheng, Iona (Author) , Pai, Rish K. (Author) , Figueiredo, Jane C. (Author) , Murphy, Neil (Author) , Gunter, Marc J. (Author) , Timpson, Nicholas J. (Author) , Vincent, Emma E. (Author)
Format:	Article (Journal)
Language:	English
Published:	Dec 21, 2023
In:	eLife Year: 2023, Volume: 12, Pages: 1-26
ISSN:	2050-084X
DOI:	10.7554/eLife.87894.3
Online Access:	Resolving-System, lizenzpflichtig, Volltext: https://doi.org/10.7554/eLife.87894.3 Verlag, lizenzpflichtig, Volltext: https://elifesciences.org/articles/87894
Author Notes:	Caroline Bull, Emma Hazelwood, Joshua A. Bell, Vanessa Tan, Andrei-Emil Constantinescu, Carolina Borges, Danny Legge, Kimberley Burrows, Jeroen R. Huyghe, Hermann Brenner, Sergi Castellvi-Bel, Andrew T. Chan, Sun-Seog Kweon, Loic Le Marchand, Li Li, Iona Cheng, Rish K. Pai, Jane C. Figueiredo, Neil Murphy, Marc J. Gunter, Nicholas J. Timpson, Emma E. Vincent

Description
Summary:	Increased genetic liability to colorectal cancer is associated with altered levels of circulating metabolites, including fatty acids, up to 40 years before average age of diagnosis.
Item Description:	Gesehen am 17.09.2024 Artikelversion: 3. Januar 2024
Physical Description:	Online Resource
ISSN:	2050-084X
DOI:	10.7554/eLife.87894.3