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Loss of Pip4k2c confers liver-metastatic organotropism through insulin-dependent PI3K-AKT pathway activation

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Main Authors: Rogava, Meri (Author) , Aprati, Tyler J. (Author) , Chi, Wei-Yu (Author) , Melms, Johannes C. (Author) , Hug, Clemens (Author) , Davis, Stephanie H. (Author) , Earlie, Ethan M. (Author) , Chung, Charlie (Author) , Deshmukh, Sachin K. (Author) , Wu, Sharon (Author) , Sledge, George W. (Author) , Tang, Stephen (Author) , Ho, Patricia (Author) , Amin, Amit Dipak (Author) , Caprio, Lindsay (Author) , Gurjao, Carino (Author) , Tagore, Somnath (Author) , Ngo, Bryan (Author) , Lee, Michael J. (Author) , Zanetti, Giorgia (Author) , Wang, Yiping (Author) , Chen, Sean (Author) , Ge, William (Author) , Martins Nascentes Melo, Luiza (Author) , Allies, Gabriele (Author) , Rösler, Jonas (Author) , Gibney, Goeffrey T. (Author) , Schmitz, Oliver J. (Author) , Sykes, Megan (Author) , Creusot, Rémi J. (Author) , Tüting, Thomas (Author) , Schadendorf, Dirk (Author) , Röcken, Martin (Author) , Eigentler, Thomas (Author) , Molotkov, Andrei (Author) , Mintz, Akiva (Author) , Bakhoum, Samuel F. (Author) , Beyaz, Semir (Author) , Cantley, Lewis (Author) , Sorger, Peter K. (Author) , Meckelmann, Sven Werner (Author) , Tasdogan, Alpaslan (Author) , Liu, David (Author) , Laughney, Ashley M. (Author) , Izar, Benjamin (Author)
Format: Article (Journal)
Language:English
Published: 2024
In: Nature cancer
Year: 2024, Volume: 5, Issue: 3, Pages: 433-447
ISSN:2662-1347
DOI:10.1038/s43018-023-00704-x
Online Access:Resolving-System: https://dx.doi.org/10.1038/s43018-023-00704-x
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Author Notes:Meri Rogava, Tyler J. Aprati, Wei-Yu Chi, Johannes C. Melms, Clemens Hug, Stephanie H. Davis, Ethan M. Earlie, Charlie Chung, Sachin K. Deshmukh, Sharon Wu, George Sledge, Stephen Tang, Patricia Ho, Amit Dipak Amin, Lindsay Caprio, Carino Gurjao, Somnath Tagore, Bryan Ngo, Michael J. Lee, Giorgia Zanetti, Yiping Wang, Sean Chen, William Ge, Luiza Martins Nascentes Melo, Gabriele Allies, Jonas Rösler, Goeffrey T. Gibney, Oliver J. Schmitz, Megan Sykes, Rémi J. Creusot, Thomas Tüting, Dirk Schadendorf, Martin Röcken, Thomas K. Eigentler, Andrei Molotkov, Akiva Mintz, Samuel F. Bakhoum, Semir Beyaz, Lewis C. Cantley, Peter K. Sorger, Sven W. Meckelmann, Alpaslan Tasdogan, David Liu, Ashley M. Laughney & Benjamin Izar
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Physical Description:Online Resource
ISSN:2662-1347
DOI:10.1038/s43018-023-00704-x

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