Test-retest reliability of the Impact of Vision Impairment-Very Low Vision questionnaire: retina

Most patient-reported outcome measures used in ophthalmology show floor effects in a very low vision population, which limits their use in vision restoration trials. The Impact of Vision Impairment-Very Low Vision scale (IVI-VLV) was developed to specifically target a very low vision population, but...

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Main Authors: Fink, David (Author) , Terheyden, Jan H. (Author) , Pondorfer, Susanne G. (Author) , Holz, Frank G. (Author) , Finger, Robert P. (Author)
Format: Article (Journal)
Language:English
Published: June 12, 2023
In: Translational Vision Science & Technology
Year: 2023, Volume: 12, Issue: 6, Pages: 1-7
ISSN:2164-2591
DOI:10.1167/tvst.12.6.6
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1167/tvst.12.6.6
Verlag, kostenfrei, Volltext: https://tvst.arvojournals.org/article.aspx?articleid=2785692
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Author Notes:David J. Fink, Jan H. Terheyden, Susanne G. Pondorfer, Frank G. Holz, and Robert P. Finger

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520 |a Most patient-reported outcome measures used in ophthalmology show floor effects in a very low vision population, which limits their use in vision restoration trials. The Impact of Vision Impairment-Very Low Vision scale (IVI-VLV) was developed to specifically target a very low vision population, but its test-retest reliability has not been investigated yet. The German version of the IVI-VLV was administered twice to patients with stable disease of a low vision clinic. Test and retest person measures of the IVI-VLV subscales were obtained from Rasch analysis. Test-retest reliability was investigated by intraclass correlation coefficients and Bland-Altman plots. We included 134 patients (72 women, 62 men) at a mean age of 62 ± 15 years. The intraclass correlation coefficients were 0.920 (95% confidence interval, 0.888-0.944) for the activities of daily living and mobility subscale of the IVI-VLV and 0.929 (95% confidence interval, 0.899-0.949) for the emotional well-being subscale. Bland-Altman plots did not indicate any systematic bias. In linear regression analysis, test-retest differences were not significantly associated with visual acuity or administration interval. Both subscales of the IVI-VLV showed excellent repeatability independent of visual acuity and length of repeat interval. Further validation steps including an assessment of the patient-reported outcome measure's responsiveness are required for use in vision restoration trials. The results support repeated use of the IVI-VLV as a patient-reported end point in future studies in very low and ultralow vision populations. 
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