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Correcting the drug development paradigm for glioblastoma requires serial tissue sampling

A breakthrough in drug discovery for glioblastoma requires serial collection of tissue from the central nervous system via window of opportunity trials

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Main Authors: Singh, Kirit (Author) , Hotchkiss, Kelly M. (Author) , Parney, Ian F. (Author) , De Groot, John (Author) , Sahebjam, Solmaz (Author) , Sanai, Nader (Author) , Platten, Michael (Author) , Galanis, Evanthia (Author) , Lim, Michael (Author) , Wen, Patrick Y. (Author) , Minniti, Giuseppe (Author) , Colman, Howard (Author) , Cloughesy, Timothy F. (Author) , Mehta, Minesh P. (Author) , Geurts, Marjolein (Author) , Arrillaga-Romany, Isabel (Author) , Desjardins, Annick (Author) , Tanner, Kirk (Author) , Short, Susan (Author) , Arons, David (Author) , Duke, Elizabeth (Author) , Wick, Wolfgang (Author) , Bagley, Stephen J. (Author) , Ashley, David M. (Author) , Kumthekar, Priya (Author) , Verhaak, Roel (Author) , Chalmers, Anthony J. (Author) , Patel, Anoop P. (Author) , Watts, Colin (Author) , Fecci, Peter E. (Author) , Batchelor, Tracy T. (Author) , Weller, Michael (Author) , Vogelbaum, Michael A. (Author) , Preusser, Matthias (Author) , Berger, Mitchel S. (Author) , Khasraw, Mustafa (Author)
Format: Article (Journal) Editorial
Language:English
Published: October 2023
In: Nature medicine
Year: 2023, Volume: 29, Issue: 10, Pages: 2402-2405
ISSN:1546-170X
DOI:10.1038/s41591-023-02464-8
Online Access:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1038/s41591-023-02464-8
Verlag, lizenzpflichtig, Volltext: https://www.nature.com/articles/s41591-023-02464-8
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Author Notes:Kirit Singh, Kelly M. Hotchkiss, Ian F. Parney, John De Groot, Solmaz Sahebjam, Nader Sanai, Michael Platten, Evanthia Galanis, Michael Lim, Patrick Y. Wen, Giuseppe Minniti, Howard Colman, Timothy F. Cloughesy, Minesh P. Mehta, Marjolein Geurts, Isabel Arrillaga-Romany, Annick Desjardins, Kirk Tanner, Susan Short, David Arons, Elizabeth Duke, Wolfgang Wick, Stephen J. Bagley, David M. Ashley, Priya Kumthekar, Roel Verhaak, Anthony J. Chalmers, Anoop P. Patel, Colin Watts, Peter E. Fecci, Tracy T. Batchelor, Michael Weller, Michael A. Vogelbaum, Matthias Preusser, Mitchel S. Berger & Mustafa Khasraw

MARC

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