Long-term evaluation of the sape of the rconstructed daphragm in ptients with left-sided congenital diaphragmatic Hernia using serial chest radiographs and correlation to further complications
Background: Defining risk factors for long-term comorbidities in patients after neonatal repair of congenital diaphragmatic hernia (CDH) is an important cornerstone of the implementation of targeted longitudinal follow-up programs. Methods: This study systematically assessed serial chest radiographs...
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| Hauptverfasser: | , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
22 January 2024
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| In: |
Journal of Clinical Medicine
Year: 2024, Jahrgang: 13, Heft: 2, Pages: 1-16 |
| ISSN: | 2077-0383 |
| DOI: | 10.3390/jcm13020620 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.3390/jcm13020620 Verlag, kostenfrei, Volltext: https://www.mdpi.com/2077-0383/13/2/620 
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| Verfasserangaben: | Christoph von Schrottenberg, Maren Lindacker, Meike Weis, Sylvia Büttner, Thomas Schaible, Michael Boettcher, Lucas M. Wessel and Katrin B. Zahn |
MARC
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| 245 | 1 | 0 | |a Long-term evaluation of the sape of the rconstructed daphragm in ptients with left-sided congenital diaphragmatic Hernia using serial chest radiographs and correlation to further complications |c Christoph von Schrottenberg, Maren Lindacker, Meike Weis, Sylvia Büttner, Thomas Schaible, Michael Boettcher, Lucas M. Wessel and Katrin B. Zahn |
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| 520 | |a Background: Defining risk factors for long-term comorbidities in patients after neonatal repair of congenital diaphragmatic hernia (CDH) is an important cornerstone of the implementation of targeted longitudinal follow-up programs. Methods: This study systematically assessed serial chest radiographs of 89 patients with left-sided CDH throughout a mean follow-up of 8.2 years. These geometrical variables for the left and right side were recorded: diaphragmatic angle (LDA, RDA), diaphragmatic diameter (LDD, RDD), diaphragmatic height (LDH, RDH), diaphragmatic curvature index (LDCI, RDCI), lower lung diameter (LLLD, RLLD) and thoracic area (LTA, RTA). Results: It was demonstrated that the shape of the diaphragm in patients with large defects systematically differs from that of patients with small defects. Characteristically, patients with large defects present with a smaller LDCI (5.1 vs. 8.4, p < 0.001) at 6 months of age, which increases over time (11.4 vs. 7.0 at the age of 15.5 years, p = 0.727), representing a flattening of the patch and the attached rudimentary diaphragm as the child grows. Conclusions: Multiple variables during early follow-up were significantly associated with comorbidities such as recurrence, scoliotic curves of the spine and a reduced thoracic area. Some geometrical variables may serve as surrogate parameters for disease severity, which is associated with long-term comorbidities. | ||
| 650 | 4 | |a CDH | |
| 650 | 4 | |a chest radiographs | |
| 650 | 4 | |a comorbidities | |
| 650 | 4 | |a congenital diaphragmatic hernia | |
| 650 | 4 | |a long-term follow-up | |
| 650 | 4 | |a reconstructed diaphragm | |
| 650 | 4 | |a recurrence | |
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