Estimated pulse wave velocity and cardiovascular events in Chinese
The estimated pulse-wave velocity (ePWV) as measure for arterial wall stiffness is associated with an increased risk of cardiovascular disease (CVDs) and all-cause death in Western populations. We investigated the association between ePWV and the incidence of CVDs (myocardial infarction, cerebral in...
Gespeichert in:
| Hauptverfasser: | , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
December 2020
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| In: |
International journal of cardiology hypertension
Year: 2020, Jahrgang: 7, Pages: 1-8 |
| ISSN: | 2590-0862 |
| DOI: | 10.1016/j.ijchy.2020.100063 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.ijchy.2020.100063 Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S2590086220300409 
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| Verfasserangaben: | Chunpeng Ji, Jingli Gao, Zhe Huang, Shuohua Chen, Guodong Wang, Shouling Wu, Jost B. Jonas |
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| 245 | 1 | 0 | |a Estimated pulse wave velocity and cardiovascular events in Chinese |c Chunpeng Ji, Jingli Gao, Zhe Huang, Shuohua Chen, Guodong Wang, Shouling Wu, Jost B. Jonas |
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| 520 | |a The estimated pulse-wave velocity (ePWV) as measure for arterial wall stiffness is associated with an increased risk of cardiovascular disease (CVDs) and all-cause death in Western populations. We investigated the association between ePWV and the incidence of CVDs (myocardial infarction, cerebral infarction, cerebral hemorrhage) and all-cause death in Chinese. The community-based longitudinal Kailuan Study included 98,348 participants undergoing biennial clinical examinations. During a mean follow-up of 10.32 ± 2.14 years, 6967 CVD events (myocardial infarction, n = 1610; cerebral infarction, n = 4634; cerebral hemorrhage, n = 1071) and 9780 all-cause deaths occurred. Stratified by age, sex and presence of cardiovascular risk factors, the incidence of CVDs and all-cause death were higher (P < 0.01) in individuals with ePWV values ≥ 10 m/s than in those with ePWV values < 10 m/s. After adjusting for age, age squared and other conventional cardiovascular risk factors, an ePWV value of ≥10 m/s or each ePWV increase by 1 m/s increased (P < 0.01) the risk for CVDs by 32% (Hazard ratio (HR):1.32; 95% confidence interval (CI):1.23-1.42) and 22% (HR:1.22; 95%CI:1.18-1.27), respectively, and increased the risk for all-cause death significantly (P < 0.01) by 28% (HR:1.28; 95%CI:1.20-1.37) and 10% (HR:1.10; 95%CI:1.07-1.13), respectively. The mean brachial-ankle PWV, measured in 43,208 individuals, was 15.30 ± 3.51 cm/s, with a mean difference of 6.45 m/s (95% limits of agreement:1.24-11.7) to the ePWV. Independently of cardiovascular risk factors, ePWV was associated with CVDs and all-cause mortality in Chinese. | ||
| 650 | 4 | |a All-cause death | |
| 650 | 4 | |a Arteriosclerosis | |
| 650 | 4 | |a Blood pressure | |
| 650 | 4 | |a Brachial-ankle pulse wave velocity | |
| 650 | 4 | |a Cardiovascular disease | |
| 650 | 4 | |a Carotid-ankle pulse wave velocity | |
| 650 | 4 | |a Hypertension | |
| 650 | 4 | |a Kailuan study | |
| 650 | 4 | |a Myocardial infarction | |
| 650 | 4 | |a Pulse wave velocity | |
| 650 | 4 | |a Stroke | |
| 700 | 1 | |a Gao, Jingli |e VerfasserIn |4 aut | |
| 700 | 1 | |a Huang, Zhe |e VerfasserIn |4 aut | |
| 700 | 1 | |a Chen, Shuohua |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wang, Guodong |e VerfasserIn |4 aut | |
| 700 | 1 | |a Wu, Shouling |e VerfasserIn |4 aut | |
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