Neutrophil extracellular traps: a crucial factor in post-surgical abdominal adhesion formation
Post-surgical abdominal adhesions, although poorly understood, are highly prevalent. The molecular processes underlying their formation remain elusive. This review aims to assess the relationship between neutrophil extracellular traps (NETs) and the generation of postoperative peritoneal adhesions a...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
6 June 2024
|
| In: |
Cells
Year: 2024, Jahrgang: 13, Heft: 11, Pages: 1-21 |
| ISSN: | 2073-4409 |
| DOI: | 10.3390/cells13110991 |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.3390/cells13110991 Verlag, kostenfrei, Volltext: https://www.mdpi.com/2073-4409/13/11/991 
|
| Verfasserangaben: | Yuqing Lu, Julia Elrod, Martin Herrmann, Jasmin Knopf and Michael Boettcher |
MARC
| LEADER | 00000caa a2200000 c 4500 | ||
|---|---|---|---|
| 001 | 1906297169 | ||
| 003 | DE-627 | ||
| 005 | 20241205181722.0 | ||
| 007 | cr uuu---uuuuu | ||
| 008 | 241021s2024 xx |||||o 00| ||eng c | ||
| 024 | 7 | |a 10.3390/cells13110991 |2 doi | |
| 035 | |a (DE-627)1906297169 | ||
| 035 | |a (DE-599)KXP1906297169 | ||
| 035 | |a (OCoLC)1475316185 | ||
| 040 | |a DE-627 |b ger |c DE-627 |e rda | ||
| 041 | |a eng | ||
| 084 | |a 33 |2 sdnb | ||
| 100 | 1 | |a Lu, Yuqing |e VerfasserIn |0 (DE-588)1336540346 |0 (DE-627)1896037526 |4 aut | |
| 245 | 1 | 0 | |a Neutrophil extracellular traps |b a crucial factor in post-surgical abdominal adhesion formation |c Yuqing Lu, Julia Elrod, Martin Herrmann, Jasmin Knopf and Michael Boettcher |
| 264 | 1 | |c 6 June 2024 | |
| 300 | |b Illustrationen | ||
| 300 | |a 21 | ||
| 336 | |a Text |b txt |2 rdacontent | ||
| 337 | |a Computermedien |b c |2 rdamedia | ||
| 338 | |a Online-Ressource |b cr |2 rdacarrier | ||
| 500 | |a Gesehen am 21.10.2024 | ||
| 520 | |a Post-surgical abdominal adhesions, although poorly understood, are highly prevalent. The molecular processes underlying their formation remain elusive. This review aims to assess the relationship between neutrophil extracellular traps (NETs) and the generation of postoperative peritoneal adhesions and to discuss methods for mitigating peritoneal adhesions. A keyword or medical subject heading (MeSH) search for all original articles and reviews was performed in PubMed and Google Scholar. It included studies assessing peritoneal adhesion reformation after abdominal surgery from 2003 to 2023. After assessing for eligibility, the selected articles were evaluated using the Critical Appraisal Skills Programme checklist for qualitative research. The search yielded 127 full-text articles for assessment of eligibility, of which 7 studies met our criteria and were subjected to a detailed quality review using the Critical Appraisal Skills Programme (CASP) checklist. The selected studies offer a comprehensive analysis of adhesion pathogenesis with a special focus on the role of neutrophil extracellular traps (NETs) in the development of peritoneal adhesions. Current interventional strategies are examined, including the use of mechanical barriers, advances in regenerative medicine, and targeted molecular therapies. In particular, this review emphasizes the potential of NET-targeted interventions as promising strategies to mitigate postoperative adhesion development. Evidence suggests that in addition to their role in innate defense against infections and autoimmune diseases, NETs also play a crucial role in the formation of peritoneal adhesions after surgery. Therefore, therapeutic strategies that target NETs are emerging as significant considerations for researchers. Continued research is vital to fully elucidate the relationship between NETs and post-surgical adhesion formation to develop effective treatments. | ||
| 650 | 4 | |a DNase1 | |
| 650 | 4 | |a DNase1L3 | |
| 650 | 4 | |a neutrophil extracellular traps | |
| 650 | 4 | |a peritoneal adhesion | |
| 650 | 4 | |a surgery | |
| 700 | 1 | |a Elrod, Julia |d 1987- |e VerfasserIn |0 (DE-588)1094920886 |0 (DE-627)855379847 |0 (DE-576)462865916 |4 aut | |
| 700 | 1 | |a Herrmann, Martin |d 1956- |e VerfasserIn |0 (DE-588)1209775344 |0 (DE-627)1697743897 |4 aut | |
| 700 | 1 | |a Knopf, Jasmin |e VerfasserIn |0 (DE-588)120670263X |0 (DE-627)1692977989 |4 aut | |
| 700 | 1 | |a Boettcher, Michael |d 1982- |e VerfasserIn |0 (DE-588)138309566 |0 (DE-627)696492113 |0 (DE-576)306510219 |4 aut | |
| 773 | 0 | 8 | |i Enthalten in |t Cells |d Basel : MDPI, 2012 |g 13(2024), 11, Artikel-ID 991, Seite 1-21 |h Online-Ressource |w (DE-627)718622081 |w (DE-600)2661518-6 |w (DE-576)365412112 |x 2073-4409 |7 nnas |a Neutrophil extracellular traps a crucial factor in post-surgical abdominal adhesion formation |
| 773 | 1 | 8 | |g volume:13 |g year:2024 |g number:11 |g elocationid:991 |g pages:1-21 |g extent:21 |a Neutrophil extracellular traps a crucial factor in post-surgical abdominal adhesion formation |
| 856 | 4 | 0 | |u https://doi.org/10.3390/cells13110991 |x Verlag |x Resolving-System |z kostenfrei |3 Volltext |
| 856 | 4 | 0 | |u https://www.mdpi.com/2073-4409/13/11/991 |x Verlag |z kostenfrei |3 Volltext |
| 951 | |a AR | ||
| 992 | |a 20241021 | ||
| 993 | |a Article | ||
| 994 | |a 2024 | ||
| 998 | |g 138309566 |a Boettcher, Michael |m 138309566:Boettcher, Michael |d 60000 |d 62200 |e 60000PB138309566 |e 62200PB138309566 |k 0/60000/ |k 1/60000/62200/ |p 5 |y j | ||
| 998 | |g 120670263X |a Knopf, Jasmin |m 120670263X:Knopf, Jasmin |d 60000 |d 62200 |e 60000PK120670263X |e 62200PK120670263X |k 0/60000/ |k 1/60000/62200/ |p 4 | ||
| 998 | |g 1209775344 |a Herrmann, Martin |m 1209775344:Herrmann, Martin |d 60000 |e 60000PH1209775344 |k 0/60000/ |p 3 | ||
| 998 | |g 1094920886 |a Elrod, Julia |m 1094920886:Elrod, Julia |d 60000 |d 62200 |e 60000PE1094920886 |e 62200PE1094920886 |k 0/60000/ |k 1/60000/62200/ |p 2 | ||
| 998 | |g 1336540346 |a Lu, Yuqing |m 1336540346:Lu, Yuqing |d 60000 |e 60000PL1336540346 |k 0/60000/ |p 1 |x j | ||
| 999 | |a KXP-PPN1906297169 |e 4600418549 | ||
| BIB | |a Y | ||
| SER | |a journal | ||
| JSO | |a {"physDesc":[{"extent":"21 S.","noteIll":"Illustrationen"}],"name":{"displayForm":["Yuqing Lu, Julia Elrod, Martin Herrmann, Jasmin Knopf and Michael Boettcher"]},"recId":"1906297169","relHost":[{"part":{"issue":"11","text":"13(2024), 11, Artikel-ID 991, Seite 1-21","year":"2024","pages":"1-21","volume":"13","extent":"21"},"language":["eng"],"id":{"zdb":["2661518-6"],"issn":["2073-4409"],"eki":["718622081"]},"recId":"718622081","physDesc":[{"extent":"Online-Ressource"}],"disp":"Neutrophil extracellular traps a crucial factor in post-surgical abdominal adhesion formationCells","type":{"media":"Online-Ressource","bibl":"periodical"},"origin":[{"publisherPlace":"Basel","dateIssuedKey":"2012","publisher":"MDPI","dateIssuedDisp":"2012-"}],"note":["Gesehen am 09.05.12"],"pubHistory":["1.2012 -"],"title":[{"title":"Cells","subtitle":"open access journal","title_sort":"Cells"}]}],"id":{"eki":["1906297169"],"doi":["10.3390/cells13110991"]},"title":[{"title":"Neutrophil extracellular traps","subtitle":"a crucial factor in post-surgical abdominal adhesion formation","title_sort":"Neutrophil extracellular traps"}],"note":["Gesehen am 21.10.2024"],"origin":[{"dateIssuedDisp":"6 June 2024","dateIssuedKey":"2024"}],"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"person":[{"display":"Lu, Yuqing","family":"Lu","role":"aut","given":"Yuqing"},{"given":"Julia","role":"aut","family":"Elrod","display":"Elrod, Julia"},{"display":"Herrmann, Martin","family":"Herrmann","role":"aut","given":"Martin"},{"role":"aut","given":"Jasmin","family":"Knopf","display":"Knopf, Jasmin"},{"role":"aut","given":"Michael","display":"Boettcher, Michael","family":"Boettcher"}]} | ||
| SRT | |a LUYUQINGELNEUTROPHIL6202 | ||