A descriptive review of next-generation insecticide-treated bed nets for malaria control

<p>To date, insecticide-treated bed nets are the most effective tool in preventing malaria-related morbidity and mortality. All distributed bed nets contain pyrethroid insecticides; however, widespread resistance to this class in the malaria vectors, <italic>Anopheles</italic> spp....

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Main Authors: Böhmert, Antonia L. (Author) , Logan, Rhiannon (Author) , Portwood, Natalie (Author) , Hartke, Juliane (Author) , Ingham, Victoria (Author)
Format: Article (Journal)
Language:English
Published: 28 May 2024
In: Frontiers in malaria
Year: 2024, Volume: 2, Pages: 1-8
ISSN:2813-7396
DOI:10.3389/fmala.2024.1337572
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3389/fmala.2024.1337572
Verlag, kostenfrei, Volltext: https://www.frontiersin.org/journals/malaria/articles/10.3389/fmala.2024.1337572/full
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Author Notes:Antonia L. Böhmert, Rhiannon A. E. Logan, Natalie M. Portwood, Juliane Hartke and Victoria A. Ingham

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520 |a <p>To date, insecticide-treated bed nets are the most effective tool in preventing malaria-related morbidity and mortality. All distributed bed nets contain pyrethroid insecticides; however, widespread resistance to this class in the malaria vectors, <italic>Anopheles</italic> spp., has led to the development of dual active ingredient bed nets, termed ‘next-generation bed nets’. These nets combine pyrethroids with a second chemistry, aimed at countering pyrethroid resistance. The World Health Organization (WHO) recently issued recommendations for three classes of next-generation bed nets. In this review, we report on key indicators across Africa for each net type. The results underscore a substantial variation in key indicators across Africa when comparing next-generation bed nets to traditional pyrethroid-only nets. Nevertheless, dual active ingredient bed nets generally outperform pyrethroid-only nets in a various settings. The results show that new nets are a formidable tool in malaria control, with superior performance compared to traditional pyrethroid-only nets. The variability in outcomes across Africa underscores the need for a region-specific approach, fostering a targeted and adaptive strategy for the deployment of these next-generation interventions.</p> 
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