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Electrophysiological effects of the sodium-glucose co-transporter-2 (SGLT2) inhibitor Dapagliflozin on human cardiac potassium channels

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The sodium-glucose co-transporter-2 (SGLT2) inhibitor dapagliflozin is increasingly used in the treatment of diabetes and heart failure. Dapagliflozin has been associated with reduced incidence of atrial fibrillation (AF) in clinical trials. We hypothesized that the favorable antiarrhythmic outcome...

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Main Authors: Müller, Mara Elena (Author) , Petersenn, Finn (Author) , Hackbarth, Juline (Author) , Pfeiffer, Julia (Author) , Gampp, Heike (Author) , Frey, Norbert (Author) , Lugenbiel, Patrick (Author) , Thomas, Dierk (Author) , Rahm, Ann-Kathrin (Author)
Format: Article (Journal)
Language:English
Published: 23 May 2024
In: International journal of molecular sciences
Year: 2024, Volume: 25, Issue: 11, Pages: 1-14
ISSN:1422-0067
DOI:10.3390/ijms25115701
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.3390/ijms25115701
Verlag, kostenfrei, Volltext: https://www.mdpi.com/1422-0067/25/11/5701
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Author Notes:Mara Elena Müller, Finn Petersenn, Juline Hackbarth, Julia Pfeiffer, Heike Gampp, Norbert Frey, Patrick Lugenbiel, Dierk Thomas and Ann-Kathrin Rahm
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Pak2 regulation of Nrf2 serves as a novel signaling nexus linking ER stress response and oxidative stress in the heart by Binder, Pablo (Author) , Nguyen, Binh (Author) , Collins, Lucy (Author) , Zi, Min (Author) , Liu, Wei (Author) , Christou, Foteini (Author) , Luo, Xiaojing (Author) , Hille, Susanne S. (Author) , Frey, Norbert (Author) , Cartwright, Elizabeth J. (Author) , Chernoff, Jonathan (Author) , Müller, Oliver J. (Author) , Guan, Kaomei (Author) , Wang, Xin (Author) ,


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