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LAA occlusion is effective and safe in very high-risk atrial fibrillation patients with prior stroke: results from the multicentre German LAARGE registry

Interventional left atrial appendage occlusion (LAAO) mitigates the risk of thromboembolic events in nonvalvular atrial fibrillation (AF) patients with contraindication for long-term oral anticoagulation (OAC). Patients with prior stroke have a relevantly increased risk of recurrent stroke, so the e...

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Main Authors: Ansari, Uzair (Author) , Brachmann, Johannes (Author) , Lewalter, Thorsten (Author) , Zeymer, Uwe (Author) , Sievert, Horst (Author) , Ledwoch, Jakob (Author) , Geist, Volker (Author) , Hochadel, Matthias (Author) , Schneider, Steffen (Author) , Senges, Jochen (Author) , Akın, Ibrahim (Author) , Fastner, Christian (Author)
Format: Article (Journal)
Language:English
Published: October 2024
In: Clinical research in cardiology
Year: 2024, Volume: 113, Issue: 10, Pages: 1451-1462
ISSN:1861-0692
DOI:10.1007/s00392-024-02376-8
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1007/s00392-024-02376-8
Verlag, kostenfrei, Volltext: https://link.springer.com/article/10.1007/s00392-024-02376-8
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Author Notes:Uzair Ansari, Johannes Brachmann, Thorsten Lewalter, Uwe Zeymer, Horst Sievert, Jakob Ledwoch, Volker Geist, Matthias Hochadel, Steffen Schneider, Jochen Senges, Ibrahim Akin, Christian Fastner
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Summary:Interventional left atrial appendage occlusion (LAAO) mitigates the risk of thromboembolic events in nonvalvular atrial fibrillation (AF) patients with contraindication for long-term oral anticoagulation (OAC). Patients with prior stroke have a relevantly increased risk of recurrent stroke, so the effectiveness of LAAO could be reduced in this specific very high-risk patient group.
Item Description:Online veröffentlicht: 31. Januar 2024
Gesehen am 25.11.2024
Physical Description:Online Resource
ISSN:1861-0692
DOI:10.1007/s00392-024-02376-8

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