MethSCAn: accurate exploratory analysis of single-cell methylomes: research briefing
Single-cell bisulfite sequencing enables the genome-wide quantification of DNA methylation at single-cell resolution, but methods to analyze the resulting data are lacking. The MethSCAn software accurately distinguishes cell types and states by scanning the genome for informative regions and providi...
Gespeichert in:
| 1. Verfasser: | |
|---|---|
| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
September 2024
|
| In: |
Nature methods
Year: 2024, Jahrgang: 21, Heft: 9, Pages: 1595-1596 |
| ISSN: | 1548-7105 |
| DOI: | 10.1038/s41592-024-02348-w |
| Online-Zugang: | Verlag, kostenfrei, Volltext: https://doi.org/10.1038/s41592-024-02348-w Verlag, kostenfrei, Volltext: https://www.nature.com/articles/s41592-024-02348-w 
|
| Verfasserangaben: | Lukas P.M. Kremer |
| Zusammenfassung: | Single-cell bisulfite sequencing enables the genome-wide quantification of DNA methylation at single-cell resolution, but methods to analyze the resulting data are lacking. The MethSCAn software accurately distinguishes cell types and states by scanning the genome for informative regions and providing a robust approach to quantifying methylation within these regions. |
|---|---|
| Beschreibung: | Veröffentlicht am 31. Juli 2024 Gesehen am 26.11.2024 This is a summary of: Kremer, L. P. M. et al. Analyzing single-cell bisulfite sequencing data with MethSCAn. Nat. Methods https://doi.org/10.1038/s41592-024-02347-x (2024) |
| Beschreibung: | Online Resource |
| ISSN: | 1548-7105 |
| DOI: | 10.1038/s41592-024-02348-w |