Cover Image

A 5:2 intermittent fasting regimen ameliorates NASH and fibrosis and blunts HCC development via hepatic PPARα and PCK1

Show other versions (1)

The role and molecular mechanisms of intermittent fasting (IF) in non-alcoholic steatohepatitis (NASH) and its transition to hepatocellular carcinoma (HCC) are unknown. Here, we identified that an IF 5:2 regimen prevents NASH development as well as ameliorates established NASH and fibrosis without a...

Full description

Saved in:
Bibliographic Details
Main Authors: Gallage, Suchira (Author) , Ali, Sheikh Adnan (Author) , Barragan Avila, José Efren (Author) , Seymen, Nogayhan (Author) , Ramadori, Pierluigi (Author) , Joerke, Vera (Author) , Zizmare, Laimdota (Author) , Aicher, David (Author) , Gopalsamy, Indresh K. (Author) , Fong, Winnie (Author) , Kosla, Jan (Author) , Focaccia, Enrico (Author) , Li, Xin (Author) , Yousuf, Suhail (Author) , Sijmonsma, Tjeerd (Author) , Rahbari, Mohammad (Author) , Kommoss, Katharina (Author) , Billeter, Adrian (Author) , Prokosch, Sandra (Author) , Rothermel, Ulrike (Author) , Mueller, Florian (Author) , Hetzer, Jenny (Author) , Heide, Danijela (Author) , Schinkel, Benjamin (Author) , Machauer, Tim (Author) , Pichler, Bernd (Author) , Malek, Nisar Peter (Author) , Longerich, Thomas (Author) , Roth, Susanne (Author) , Rose, Adam J. (Author) , Schwenck, Johannes (Author) , Trautwein, Christoph (Author) , Karimi, Mohammad M. (Author) , Heikenwälder, Mathias (Author)
Format: Article (Journal)
Language:English
Published: 4 June 2024
In: Cell metabolism
Year: 2024, Volume: 36, Issue: 6, Pages: 1371-1393.e7
ISSN:1932-7420
DOI:10.1016/j.cmet.2024.04.015
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1016/j.cmet.2024.04.015
Verlag, kostenfrei, Volltext: https://www.sciencedirect.com/science/article/pii/S1550413124001359
Get full text
Author Notes:Suchira Gallage, Adnan Ali, Jose Efren Barragan Avila, Nogayhan Seymen, Pierluigi Ramadori, Vera Joerke, Laimdota Zizmare, David Aicher, Indresh K. Gopalsamy, Winnie Fong, Jan Kosla, Enrico Focaccia, Xin Li, Suhail Yousuf, Tjeerd Sijmonsma, Mohammad Rahbari, Katharina S. Kommoss, Adrian Billeter, Sandra Prokosch, Ulrike Rothermel, Florian Mueller, Jenny Hetzer, Danijela Heide, Benjamin Schinkel, Tim Machauer, Bernd Pichler, Nisar P. Malek, Thomas Longerich, Susanne Roth, Adam J. Rose, Johannes Schwenck, Christoph Trautwein, Mohammad M. Karimi, and Mathias Heikenwalder
Search Result 1
Cover Image

Hepatocyte-specific NRF2 activation controls fibrogenesis and carcinogenesis in steatohepatitis by Mohs, Antje (Author) , Otto, Tobias (Author) , Schneider, Kai Markus (Author) , Peltzer, Mona (Author) , Boekschoten, Mark (Author) , Holland, Christian H. (Author) , Hudert, Christian A. (Author) , Kalveram, Laura (Author) , Wiegand, Susanna (Author) , Sáez Rodríguez, Julio (Author) , Longerich, Thomas (Author) , Hengstler, Jan G. (Author) , Trautwein, Christian (Author) ,


Get full text
Article (Journal) Online Resource

Saved in:
Show all versions (2)

Similar Items