The morphology strikes back
“Molecular trumps morphology” was the slogan for the WHO classification of Central Nervous System (CNS) tumors updated in 2016 (CNS4+) and is even more applicable for the current WHO classification (CNS5).1,2 As one of many implications, albeit certainly not the clinically most far-reaching, neuropa...
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| Main Author: | |
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| Format: | Article (Journal) Editorial |
| Language: | English |
| Published: |
September 2024
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| In: |
Neuro-Oncology
Year: 2024, Volume: 26, Issue: 9, Pages: 1543-1544 |
| ISSN: | 1523-5866 |
| DOI: | 10.1093/neuonc/noae124 |
| Online Access: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/neuonc/noae124 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/neuro-oncology/article/26/9/1543/7713108 
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| Author Notes: | Felix Sahm |
| Summary: | “Molecular trumps morphology” was the slogan for the WHO classification of Central Nervous System (CNS) tumors updated in 2016 (CNS4+) and is even more applicable for the current WHO classification (CNS5).1,2 As one of many implications, albeit certainly not the clinically most far-reaching, neuropathologists are asked whether they even need H&E sections anymore (which often is only a covert attempt to question the need for the neuropathologists themselves). On the contrary, how all these novel tests underlying the newly introduced biomarkers can be afforded in routine care is a pressing question, given the typically large equipment and reagent cost. In fact, these requirements have even been debated as incompatible with the goals and mandate of a World Health Organization guideline.3,4 |
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| Item Description: | Online veröffentlicht: 13. Juli 2024 Gesehen am 29.11.2024 |
| Physical Description: | Online Resource |
| ISSN: | 1523-5866 |
| DOI: | 10.1093/neuonc/noae124 |