The morphology strikes back
“Molecular trumps morphology” was the slogan for the WHO classification of Central Nervous System (CNS) tumors updated in 2016 (CNS4+) and is even more applicable for the current WHO classification (CNS5).1,2 As one of many implications, albeit certainly not the clinically most far-reaching, neuropa...
Gespeichert in:
| 1. Verfasser: | |
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| Dokumenttyp: | Article (Journal) Editorial |
| Sprache: | Englisch |
| Veröffentlicht: |
September 2024
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| In: |
Neuro-Oncology
Year: 2024, Jahrgang: 26, Heft: 9, Pages: 1543-1544 |
| ISSN: | 1523-5866 |
| DOI: | 10.1093/neuonc/noae124 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1093/neuonc/noae124 Verlag, lizenzpflichtig, Volltext: https://academic.oup.com/neuro-oncology/article/26/9/1543/7713108 |
| Verfasserangaben: | Felix Sahm |
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| 520 | |a “Molecular trumps morphology” was the slogan for the WHO classification of Central Nervous System (CNS) tumors updated in 2016 (CNS4+) and is even more applicable for the current WHO classification (CNS5).1,2 As one of many implications, albeit certainly not the clinically most far-reaching, neuropathologists are asked whether they even need H&E sections anymore (which often is only a covert attempt to question the need for the neuropathologists themselves). On the contrary, how all these novel tests underlying the newly introduced biomarkers can be afforded in routine care is a pressing question, given the typically large equipment and reagent cost. In fact, these requirements have even been debated as incompatible with the goals and mandate of a World Health Organization guideline.3,4 | ||
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