Neural deception: breast cancer co-opts neuronal mechanisms to evade the immune system
Cellular mechanisms mediating immunotherapy resistances are incompletely understood. In this issue, Li et al. reveal how breast cancer hijacks neuronal mechanisms of neuroprotection to shield itself from the immune system. Secretion of N-acetylaspartate impairs immune synapse formation in both neuro...
Gespeichert in:
| Hauptverfasser: | , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
30 May 2024
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| In: |
Cancer cell
Year: 2024, Jahrgang: 42, Heft: 6, Pages: 936-938 |
| ISSN: | 1878-3686 |
| DOI: | 10.1016/j.ccell.2024.05.007 |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1016/j.ccell.2024.05.007 Verlag, lizenzpflichtig, Volltext: https://www.sciencedirect.com/science/article/pii/S1535610824001703 
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| Verfasserangaben: | Nikolas Layer, Lukas Bunse, and Varun Venkataramani |
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| 520 | |a Cellular mechanisms mediating immunotherapy resistances are incompletely understood. In this issue, Li et al. reveal how breast cancer hijacks neuronal mechanisms of neuroprotection to shield itself from the immune system. Secretion of N-acetylaspartate impairs immune synapse formation in both neuroinflammation and breast cancer models, paving the way for novel therapeutic approaches. | ||
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