Characteristics of H3K27M-mutant diffuse gliomas with a non-midline location
Diffuse midline gliomas (DMG) with H3K27 alterations (H3K27M-DMG) are a highly aggressive form of brain cancer. In rare cases, H3K27 mutations have been observed in diffuse non-midline gliomas (DNMG). It is currently unclear how these tumors should be classified. Herein, we analyze the characteristi...
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| Hauptverfasser: | , , , , , , , , , , , , , , |
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| Dokumenttyp: | Article (Journal) |
| Sprache: | Englisch |
| Veröffentlicht: |
27 June 2024
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| In: |
Journal of neuro-oncology
Year: 2024, Jahrgang: 169, Heft: 2, Pages: 391-398 |
| ISSN: | 1573-7373 |
| DOI: | 10.1007/s11060-024-04733-z |
| Online-Zugang: | Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/s11060-024-04733-z
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| Verfasserangaben: | Souhir Guidara, Antoine Seyve, Delphine Poncet, Camille Leonce, Pierre-Paul Bringuier, Anne McLeer, Dominik Sturm, Stéphanie Cartalat, Thiebaud Picart, Anthony Ferrari, Jürgen Hench, Stephan Frank, David Meyronet, François Ducray, Marc Barritault |
MARC
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| 520 | |a Diffuse midline gliomas (DMG) with H3K27 alterations (H3K27M-DMG) are a highly aggressive form of brain cancer. In rare cases, H3K27 mutations have been observed in diffuse non-midline gliomas (DNMG). It is currently unclear how these tumors should be classified. Herein, we analyze the characteristics of DNMG with H3K27M mutations. | ||
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| 650 | 4 | |a Methylation | |
| 650 | 4 | |a Non-midline | |
| 650 | 4 | |a Pediatric glioma | |
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