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Does compulsion explain addiction?: opinion

One of the leading drug addiction theories states that habits and the underlying neural process of a ventral to dorsal striatal shift are the building blocks of compulsive drug-seeking behaviour and that compulsion is the maladaptive persistence of responding despite adverse consequences. Here we di...

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Bibliographic Details
Main Authors: Heinz, Andreas (Author) , Gutwinski, Stefan (Author) , Bahr, Nadja Samia (Author) , Spanagel, Rainer (Author) , Di Chiara, Gaetano (Author)
Format: Article (Journal)
Language:English
Published: April 2024
In: Addiction biology
Year: 2024, Volume: 29, Issue: 4, Pages: 1-5
ISSN:1369-1600
DOI:10.1111/adb.13379
Online Access:Verlag, kostenfrei, Volltext: https://doi.org/10.1111/adb.13379
Verlag, kostenfrei, Volltext: http://onlinelibrary.wiley.com/doi/abs/10.1111/adb.13379
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Author Notes:Andreas Heinz, Stefan Gutwinski, Nadja Samia Bahr, Rainer Spanagel, Gaetano Di Chiara
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Summary:One of the leading drug addiction theories states that habits and the underlying neural process of a ventral to dorsal striatal shift are the building blocks of compulsive drug-seeking behaviour and that compulsion is the maladaptive persistence of responding despite adverse consequences. Here we discuss that compulsive behaviour as defined primarily from the perspective of animal experimentation falls short of the clinical phenomena and their neurobiological correlates. Thus for the human condition, the concept of compulsive habits should be critically addressed and potentially revised.
Item Description:Erstmals veröffentlicht: 08. April 2024
Gesehen am 28.01.2025
Physical Description:Online Resource
ISSN:1369-1600
DOI:10.1111/adb.13379

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