Serum amyloid A protein (SAA): a marker for liver allograft rejection in humans

Serum amyloid A protein (SAA) concentrations were monitored in 12 consecutive liver transplant recipients until the 70th postoperative day. Fourteen rejection episodes were identified histologically in 42 liver biopsies of the grafts. Of 12 rejections 8 (66.7%) were characterized by pronounced simul...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Feussner, Giso (VerfasserIn) , Stech, Christine (VerfasserIn) , Dobmeyer, Jürgen (VerfasserIn) , Schaefer, H. (VerfasserIn) , Otto, Gerd (VerfasserIn) , Ziegler, Reinhard (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: December 1994
In: Journal of molecular medicine
Year: 1994, Jahrgang: 72, Heft: 12, Pages: 1007-1011
ISSN:1432-1440
DOI:10.1007/BF00577745
Online-Zugang:Verlag, lizenzpflichtig, Volltext: https://doi.org/10.1007/BF00577745
Volltext
Verfasserangaben:G. Feussner, C. Stech, J. Dobmeyer, H. Schaefer, G. Otto, R. Ziegler

MARC

LEADER 00000caa a2200000 c 4500
001 1915996333
003 DE-627
005 20250716225409.0
007 cr uuu---uuuuu
008 250130s1994 xx |||||o 00| ||eng c
024 7 |a 10.1007/BF00577745  |2 doi 
035 |a (DE-627)1915996333 
035 |a (DE-599)KXP1915996333 
035 |a (OCoLC)1528018126 
040 |a DE-627  |b ger  |c DE-627  |e rda 
041 |a eng 
084 |a 33  |2 sdnb 
100 1 |a Feussner, Giso  |e VerfasserIn  |0 (DE-588)1111522685  |0 (DE-627)865591776  |0 (DE-576)476134900  |4 aut 
245 1 0 |a Serum amyloid A protein (SAA)  |b a marker for liver allograft rejection in humans  |c G. Feussner, C. Stech, J. Dobmeyer, H. Schaefer, G. Otto, R. Ziegler 
264 1 |c December 1994 
300 |a 5 
336 |a Text  |b txt  |2 rdacontent 
337 |a Computermedien  |b c  |2 rdamedia 
338 |a Online-Ressource  |b cr  |2 rdacarrier 
500 |a Gesehen am 30.01.2025 
520 |a Serum amyloid A protein (SAA) concentrations were monitored in 12 consecutive liver transplant recipients until the 70th postoperative day. Fourteen rejection episodes were identified histologically in 42 liver biopsies of the grafts. Of 12 rejections 8 (66.7%) were characterized by pronounced simultaneous increases in SAA concentrations in plasma, the mean peak value being 16.94 ± 8.82 mg/dl (range 4.58-28.55 mg/dl) compared with a mean normal value of 0.98 ±0.42 mg/dl in healthy controls. Of 42 biopsies 28 did not show histological evidence of graft rejection. Of 25 negative biopsies 24 (96.0%) were not accompanied by a parallel SAA increase in plasma. These findings demonstrate that measurements of SAA concentrations may provide a valuable non-invasive aid in identifying acute liver allograft rejection in humans. 
650 4 |a Acute phase reaction 
650 4 |a Allograft rejection 
650 4 |a Liver transplantation 
650 4 |a Serum amyloid A protein 
700 1 |a Stech, Christine  |e VerfasserIn  |4 aut 
700 1 |a Dobmeyer, Jürgen  |e VerfasserIn  |0 (DE-588)1354065549  |0 (DE-627)1915389410  |4 aut 
700 1 |a Schaefer, H.  |e VerfasserIn  |4 aut 
700 1 |a Otto, Gerd  |d 1944-  |e VerfasserIn  |0 (DE-588)1235891895  |0 (DE-627)1761126156  |4 aut 
700 1 |a Ziegler, Reinhard  |d 1935-  |e VerfasserIn  |0 (DE-588)115545344  |0 (DE-627)077320182  |0 (DE-576)289941652  |4 aut 
773 0 8 |i Enthalten in  |t Journal of molecular medicine  |d Berlin : Springer, 1995  |g 72(1994), 12, Seite 1007-1011  |h Online-Ressource  |w (DE-627)254630804  |w (DE-600)1462132-0  |w (DE-576)079420028  |x 1432-1440  |7 nnas  |a Serum amyloid A protein (SAA) a marker for liver allograft rejection in humans 
773 1 8 |g volume:72  |g year:1994  |g number:12  |g pages:1007-1011  |g extent:5  |a Serum amyloid A protein (SAA) a marker for liver allograft rejection in humans 
856 4 0 |u https://doi.org/10.1007/BF00577745  |x Verlag  |x Resolving-System  |z lizenzpflichtig  |3 Volltext 
951 |a AR 
992 |a 20250130 
993 |a Article 
994 |a 1994 
998 |g 115545344  |a Ziegler, Reinhard  |m 115545344:Ziegler, Reinhard  |d 910000  |d 910100  |e 910000PZ115545344  |e 910100PZ115545344  |k 0/910000/  |k 1/910000/910100/  |p 6  |y j 
998 |g 1235891895  |a Otto, Gerd  |m 1235891895:Otto, Gerd  |d 910000  |d 910200  |e 910000PO1235891895  |e 910200PO1235891895  |k 0/910000/  |k 1/910000/910200/  |p 5 
998 |g 1354065549  |a Dobmeyer, Jürgen  |m 1354065549:Dobmeyer, Jürgen  |d 910000  |d 910100  |e 910000PD1354065549  |e 910100PD1354065549  |k 0/910000/  |k 1/910000/910100/  |p 3 
998 |g 1111522685  |a Feussner, Giso  |m 1111522685:Feussner, Giso  |d 910000  |d 910100  |e 910000PF1111522685  |e 910100PF1111522685  |k 0/910000/  |k 1/910000/910100/  |p 1  |x j 
999 |a KXP-PPN1915996333  |e 4659237532 
BIB |a Y 
SER |a journal 
JSO |a {"type":{"media":"Online-Ressource","bibl":"article-journal"},"language":["eng"],"relHost":[{"title":[{"title_sort":"Journal of molecular medicine","title":"Journal of molecular medicine"}],"origin":[{"publisher":"Springer","dateIssuedDisp":"1995-","dateIssuedKey":"1995","publisherPlace":"Berlin ; Heidelberg ; New York, NY"}],"disp":"Serum amyloid A protein (SAA) a marker for liver allograft rejection in humansJournal of molecular medicine","part":{"text":"72(1994), 12, Seite 1007-1011","extent":"5","volume":"72","pages":"1007-1011","year":"1994","issue":"12"},"language":["eng"],"type":{"media":"Online-Ressource","bibl":"periodical"},"id":{"eki":["254630804"],"zdb":["1462132-0"],"issn":["1432-1440"]},"recId":"254630804","physDesc":[{"extent":"Online-Ressource"}],"note":["Gesehen am 14.03.25"],"pubHistory":["Volume 73, issue 1 (January 1995)-"]}],"origin":[{"dateIssuedKey":"1994","dateIssuedDisp":"December 1994"}],"title":[{"subtitle":"a marker for liver allograft rejection in humans","title":"Serum amyloid A protein (SAA)","title_sort":"Serum amyloid A protein (SAA)"}],"name":{"displayForm":["G. Feussner, C. Stech, J. Dobmeyer, H. Schaefer, G. Otto, R. Ziegler"]},"person":[{"given":"Giso","family":"Feussner","roleDisplay":"VerfasserIn","display":"Feussner, Giso","role":"aut"},{"display":"Stech, Christine","role":"aut","roleDisplay":"VerfasserIn","family":"Stech","given":"Christine"},{"given":"Jürgen","family":"Dobmeyer","roleDisplay":"VerfasserIn","display":"Dobmeyer, Jürgen","role":"aut"},{"roleDisplay":"VerfasserIn","display":"Schaefer, H.","role":"aut","given":"H.","family":"Schaefer"},{"display":"Otto, Gerd","role":"aut","roleDisplay":"VerfasserIn","given":"Gerd","family":"Otto"},{"role":"aut","display":"Ziegler, Reinhard","roleDisplay":"VerfasserIn","family":"Ziegler","given":"Reinhard"}],"note":["Gesehen am 30.01.2025"],"physDesc":[{"extent":"5 S."}],"recId":"1915996333","id":{"eki":["1915996333"],"doi":["10.1007/BF00577745"]}} 
SRT |a FEUSSNERGISERUMAMYLO1994