Inter-facility transfers for emergency obstetrical and neonatal care in rural Madagascar: a cost-effectiveness analysis

CONTEXT: There is a substantial lack of inter-facility referral systems for emergency obstetrical and neonatal care in rural areas of sub-Saharan Africa. Data on the costs and cost-effectiveness of such systems that reduce preventable maternal and neonatal deaths are scarce. - SETTING: We aimed to d...

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Hauptverfasser: Franke, Mara Anna (VerfasserIn) , Nordmann, Kim (VerfasserIn) , Frühauf, Anna (VerfasserIn) , Ranaivoson, Rinja Mitolotra (VerfasserIn) , Rebaliha, Mahery (VerfasserIn) , Rapanjato, Zavaniarivo (VerfasserIn) , Bärnighausen, Till (VerfasserIn) , Muller, Nadine (VerfasserIn) , Knauss, Samuel (VerfasserIn) , Emmrich, Julius (VerfasserIn)
Dokumenttyp: Article (Journal)
Sprache:Englisch
Veröffentlicht: 3 April 2024
In: BMJ open
Year: 2024, Jahrgang: 14, Heft: 4, Pages: 1-9
ISSN:2044-6055
DOI:10.1136/bmjopen-2023-081482
Online-Zugang:Verlag, kostenfrei, Volltext: https://doi.org/10.1136/bmjopen-2023-081482
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Verfasserangaben:Mara Anna Franke, Kim Nordmann, Anna Frühauf, Rinja Mitolotra Ranaivoson, Mahery Rebaliha, Zavaniarivo Rapanjato, Till Bärnighausen, Nadine Muller, Samuel Knauss, Julius Valentin Emmrich

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520 |a CONTEXT: There is a substantial lack of inter-facility referral systems for emergency obstetrical and neonatal care in rural areas of sub-Saharan Africa. Data on the costs and cost-effectiveness of such systems that reduce preventable maternal and neonatal deaths are scarce. - SETTING: We aimed to determine the cost-effectiveness of a non-governmental organisation (NGO)-run inter-facility referral system for emergency obstetrical and neonatal care in rural Southern Madagascar by analysing the characteristics of cases referred through the intervention as well as its costs. - DESIGN: We used secondary NGO data, drawn from an NGO's monitoring and financial administration database, including medical and financial records. - OUTCOME MEASURES: We performed a descriptive and a cost-effectiveness analysis, including a one-way deterministic sensitivity analysis. - RESULTS: 1172 cases were referred over a period of 4 years. The most common referral reasons were obstructed labour, ineffective labour and eclampsia. In total, 48 neonates were referred through the referral system over the study period. Estimated cost per referral was US$336 and the incremental cost-effectiveness ratio (ICER) was US$70 per additional life-year saved (undiscounted, discounted US$137). The sensitivity analysis showed that the intervention was cost-effective for all scenarios with the lowest ICER at US$99 and the highest ICER at US$205 per additional life-year saved. When extrapolated to the population living in the study area, the investment costs of the programme were US$0.13 per person and annual running costs US$0.06 per person. - CONCLUSIONS: In our study, the inter-facility referral system was a very cost-effective intervention. Our findings may inform policies, decision-making and implementation strategies for emergency obstetrical and neonatal care referral systems in similar resource-constrained settings. 
650 4 |a ACCIDENT & EMERGENCY MEDICINE 
650 4 |a Cost-Benefit Analysis 
650 4 |a Cost-Effectiveness Analysis 
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650 4 |a Health economics 
650 4 |a Humans 
650 4 |a Infant, Newborn 
650 4 |a Labor, Obstetric 
650 4 |a Madagascar 
650 4 |a NEONATOLOGY 
650 4 |a Obstetrics 
650 4 |a OBSTETRICS 
650 4 |a Pregnancy 
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